ArticleAnnals of translational medicine2021
The effects of heatwaves and cold spells on patients admitted with acute ischemic stroke.
Article in Annals of translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between ambient temperature and risk of stroke morbidity and mortality: A systematic review and meta-analysis.Brain and behavior · 2023Pooled it
- Barometric pressure variability and shunt-related hospital encounters in the pediatric population: a retrospective analysis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Article
- Extreme temperature events and hospitalizations for 59 autoimmune diseases in Korea: A nationwide outcome-wide, time-stratified, case-crossover study.Environmental research · 2026Article
- Associations of heatwaves and their characteristics with ischaemic stroke hospital admissions.Scientific reports · 2025Article
- Seasonal variations in admissions for atrial fibrillation or atrial flutter in the Northeast and the Midwest regions of the United States.Proceedings (Baylor University. Medical Center) · 2024Article
- Risk and attributable fraction estimation for the impact of exposure to compound drought and hot events on daily stroke admissions.Environmental health and preventive medicine · 2024Article
- Temperature variability increases the onset risk of ischemic stroke: A 10-year study in Tianjin, China.Frontiers in neurology · 2023Article
- [Cold stress reduces lifespan and mobility ofNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2022Article
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study aimed to explore the effects of heatwaves and cold spells on blood pressure, thrombus formation, and systemic inflammation at admission in patients with ischemic stroke.
methodsData of patients with ischemic stroke who were admitted to the Second Hospital of Tianjin Medical University between May 2014 and March 2019 were reviewed, along with meteorological data from the same time period. A total of 806 clinically confirmed patients with ischemic stroke (34-97 years old) were included in the final analysis. Heatwaves and cold spells were defined as ≥2 consecutive days with average temperature >95
resultsAfter adjustment for potential environmental confounders, heatwaves were positively associated with high systolic blood pressure (SBP) (β=8.693, P=0.019), diastolic blood pressure (DBP) (β=3.665, P=0.040), reduced thrombin time (TT) (β=-0.642, P=0.027), and activated partial thromboplastin time (APTT) (β=-1.572, P=0.027) in ischemic stroke patients at admission. Cold spells were positively associated with high SBP (β=5.277, P=0.028), DBP (β=4.672, P=0.012), fibrinogen (β=0.315, P=0.011), globulin (β=1.523, P=0.011), and reduced TT (β=-0.784, P<0.001) and APTT (β=-1.062, P=0.024). Cold spells were also associated with a higher risk of respiratory infection [odds ratio (OR) =2.677, P=0.001].
conclusionsExposure to heatwaves or cold spells was associated with blood pressure and coagulation at admission in patients with ischemic stroke. Cold spells also resulted in higher levels of inflammation. These findings suggest that changes in coagulation, blood pressure, and inflammation may be the potential biological mechanisms underlying the cerebrovascular effects of exposure to extreme temperatures.
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