ArticleAnnals of translational medicine2021
Evaluation of the linear interpolation method in correcting the influence of slice thicknesses on radiomic feature values in solid pulmonary nodules: a prospective patient study.
Article in Annals of translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- Differentiating Schmorl's nodes from osteolytic bone metastases: diagnostic performance of conventional CT features and CT-based models incorporating radiomics and CT features.Skeletal radiology · 2026Article
- Radiomics of Dynamic Contrast-Enhanced MRI for Predicting Radiation-Induced Hepatic Toxicity After Intensity Modulated Radiotherapy for Hepatocellular Carcinoma: A Machine Learning Predictive Model Based on the SHAP Methodology.Journal of hepatocellular carcinoma · 2025Article
- Finding Reproducible and Prognostic Radiomic Features in Variable Slice Thickness Contrast Enhanced CT of Colorectal Liver Metastases.The journal of machine learning for biomedical imaging · 2025Article
- Impact of slice thickness on reproducibility of CT radiomic features of lung tumors.F1000Research · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo investigate the influence of slice thickness on radiomic feature (RF) values in solid pulmonary nodules and evaluate the effect of a linear interpolation method in correcting the influence.
methodsThirty pulmonary nodules from 28 patients were selected prospectively with a thick-slice of 5 mm and a thin-slice of 1.25 mm on CT. A resampling method was used to normalize the voxel size of thick and thin slices CT images to 1×1×1 mm
resultsAmong the 396 RFs, 305 RFs showed an intraclass correlation coefficient ≥0.75 after test-retest analysis (including 22 histogram features, 20 geometry features, and 263 texture features). In the non-resampled data, 239 RF values (78.4%, 239/305) showed significant differences between thick and thin slice CT images. Resampling of thick images revealed that 202 RF values (66.2%, 202/305) showed significant differences between thick-r and thin slice CT images, showing a significant decrease in the number of different RF values when compared to non-resampled data (P<0.01). For the RF subgroups, only texture features showed a significant reduction in the number of different RF values after resampling (P<0.01). When both thick and thin slice images were resampled, the number of significantly different RF values between thick-r and thin-r images was increased to 247 (81.0%, 247/305), showing no significant difference when compared to non-resampled data (P=0.421).
conclusionsSlice thickness demonstrated a considerable influence on RF values in solid pulmonary nodules, producing false results when CT images with different slice thicknesses were used. Linear interpolation of the resampling method was limited because of the relatively small correction effect.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.