Evidence map›Paper›PMID 33708641›Full record

ArticleLiver cancer2021

Switching Monopolar No-Touch Radiofrequency Ablation Using Octopus Electrodes for Small Hepatocellular Carcinoma: A Randomized Clinical Trial.

Sae-Jin Park, Eun Ju Cho, Jeong-Hoon Lee, Su Jong Yu, Yoon Jun Kim, Jung-Hwan Yoon, Hyo-Jin Kang, Jeong Hee Yoon, Dong Ho Lee, Se Hyung Kim and 2 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Liver cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03375281 (Radiofrequency Ablation Using Octopus Electrodes for Small Hepatocellular Carcinoma With No-touch Technique), which is not on this map. Cited by 22 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03375281 nacompletednot on this map

Radiofrequency Ablation Using Octopus Electrodes for Small Hepatocellular Carcinoma With No-touch Technique: A Prospective Single Arm Study

TypeinterventionalSponsorSeoul National University HospitalRan2017 to 2020Enrolled140ConditionsHepatocellular Carcinoma, Radiofrequency AblationArmsRFA
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Guideline
  2. Guideline
  3. Pooled it
  4. Guideline
  5. Trial
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sae-Jin ParkDepartment of Radiology, Seoul National University Hospital, Seoul, Republic of Korea.
Eun Ju ChoDepartment of Internal Medicine and Liver Research Institute, College of Medicine, Seoul National University, Seoul, Republic of Korea.
Jeong-Hoon LeeDepartment of Internal Medicine and Liver Research Institute, College of Medicine, Seoul National University, Seoul, Republic of Korea.
Su Jong YuDepartment of Internal Medicine and Liver Research Institute, College of Medicine, Seoul National University, Seoul, Republic of Korea.
Yoon Jun KimDepartment of Internal Medicine and Liver Research Institute, College of Medicine, Seoul National University, Seoul, Republic of Korea.
Jung-Hwan YoonDepartment of Internal Medicine and Liver Research Institute, College of Medicine, Seoul National University, Seoul, Republic of Korea.
Hyo-Jin KangDepartment of Radiology, Seoul National University Hospital, Seoul, Republic of Korea.
Jeong Hee YoonDepartment of Radiology, Seoul National University Hospital, Seoul, Republic of Korea.
Dong Ho LeeDepartment of Radiology, Seoul National University Hospital, Seoul, Republic of Korea.
Se Hyung KimDepartment of Radiology, Seoul National University Hospital, Seoul, Republic of Korea.
Jae Young LeeDepartment of Radiology, Seoul National University Hospital, Seoul, Republic of Korea.
Jeong Min LeeDepartment of Radiology, Seoul National University Hospital, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionA switching monopolar no-touch radiofrequency ablation (RFA) technique is used for small hepatocellular carcinoma (HCC); however, there have not been any randomized clinical trials comparing this technique to the conventional RFA technique.

objectiveThis study aims to compare the results of two RFA techniques, and to comparatively identify more effective methods to reduce the progression of local tumors associated with small HCC (≤2.5 cm).

methodsThis prospective randomized clinical trial (NCT03375281) recruited a total of 116 participants (M:F, 93:23; 68.3 ± 8.4 years) between October 2016 and September 2017. The primary outcome was the cumulative incidence of local tumor progression (LTP) after RFA. Secondary outcomes included technical success rate, technique efficacy, and RFA procedure characteristics. Kaplan-Meier analysis and the Cox proportional hazard regression model were used.

resultsThe mean follow-up period was 24.1 months. A sufficient ablative margin was more frequently achieved in the no-touch RFA group (57/60 = 95%) than in the conventional RFA group (50/64 = 78.1%) on immediate follow-up CT (

conclusionsA switching monopolar no-touch RFA technique is a favorable treatment option and provides lower LTP after RFA compared with conventional RFA for small HCC.

Indexed as

Hepatocellular carcinomaLocal tumor progressionRadiofrequency ablation

Identifiers

PMID33708641
PMCPMC7923899

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.