Evidence map›Paper›PMID 33708636›Full record

ReviewLiver cancer2021

Diffusion-Weighted Imaging Reflects Tumor Grading and Microvascular Invasion in Hepatocellular Carcinoma.

Alexey Surov, Maciej Pech, Jazan Omari, Frank Fischbach, Robert Damm, Katharina Fischbach, Maciej Powerski, Borna Relja, Andreas Wienke

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Liver cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06168357 (Role of Abbreviated MRI in Follow-up of Hepatocellular Carcinoma Following Locoregional Treatment.), which is not on this map. Cited by 44 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 2 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06168357 not yet recruitingnot on this mapstarted 2024, after this paper: background citation

Role of Abbreviated MRI in Follow-up of Hepatocellular Carcinoma Following Locoregional Treatment.

TypeobservationalSponsorAssiut UniversityRan2024 to 2027Enrolled55ConditionsHepatocellular Carcinoma
3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 71 citations in OpenAlex.

  1. Pooled it
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  12. Prognostic and diagnostic value of [European radiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Alexey SurovDepartment of Radiology and Nuclear Medicine University of Magdeburg, Magdeburg, Germany.
Maciej PechDepartment of Radiology and Nuclear Medicine University of Magdeburg, Magdeburg, Germany.
Jazan OmariDepartment of Radiology and Nuclear Medicine University of Magdeburg, Magdeburg, Germany.
Frank FischbachDepartment of Radiology and Nuclear Medicine University of Magdeburg, Magdeburg, Germany.
Robert DammDepartment of Radiology and Nuclear Medicine University of Magdeburg, Magdeburg, Germany.
Katharina FischbachDepartment of Radiology and Nuclear Medicine University of Magdeburg, Magdeburg, Germany.
Maciej PowerskiDepartment of Radiology and Nuclear Medicine University of Magdeburg, Magdeburg, Germany.
Borna ReljaDepartment of Radiology and Nuclear Medicine University of Magdeburg, Magdeburg, Germany.
Andreas WienkeInstitute of Medical Epidemiology, Biostatistics, and Informatics, Martin-Luther-University Halle-Wittenberg, Halle, Germany.
University Hospital Magdeburg · DEMartin Luther University Halle-Wittenberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo date, there are inconsistent data about relationships between diffusion-weighted imaging (DWI) and tumor grading/microvascular invasion (MVI) in hepatocellular carcinoma (HCC). Our purpose was to systematize the reported results regarding the role of DWI in prediction of tumor grading/MVI in HCC.

methodMEDLINE library, Scopus, and Embase data bases were screened up to December 2019. Overall, 29 studies with 2,715 tumors were included into the analysis. There were 20 studies regarding DWI and tumor grading, 8 studies about DWI and MVI, and 1 study investigated DWI, tumor grading, and MVI in HCC.

resultsIn 21 studies (1,799 tumors), mean apparent diffusion coefficient (ADC) values (ADC

conclusionADC

Indexed as

Diffusion-weighted imagingGradingHepatocellular carcinomaMicrovascular invasion

Identifiers

PMID33708636
PMCPMC7923880
OpenAlexW3121418559

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.