Evidence map›Paper›PMID 33708254›Full record

ArticleJournal of oncology2021

BCL-2 (-938C>A), BAX (-248G>A), and HER2 Ile655Val Polymorphisms and Breast Cancer Risk in Indian Population.

Deepti Bhatt, Amit Kumar Verma, Prahalad Singh Bharti, Yamini Goyal, Mohammed A Alsahli, Ahmad Almatroudi, Arshad Husain Rahmani, Saleh Almatroodi, Prakash C Joshi, Mohammad Mahtab Alam and 3 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. In Silico and Wet Analysis ofCurrent issues in molecular biology · 2025
    Article
  2. Evaluation ofArchives of Razi Institute · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Deepti Bhatt *Department of Biotechnology, Jamia Millia Islamia, New Delhi, India.
Amit Kumar Verma *Department of Biotechnology, Jamia Millia Islamia, New Delhi, India.
Prahalad Singh BhartiDepartment of Biophysics, All India Institute of Medical Sciences, New Delhi, India.
Yamini GoyalDepartment of Biotechnology, Jamia Millia Islamia, New Delhi, India.
Mohammed A AlsahliDepartment of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraidah, Saudi Arabia.
Ahmad AlmatroudiDepartment of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraidah, Saudi Arabia.ORCID https://orcid.org/0000-0002-1491-6402
Arshad Husain RahmaniDepartment of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraidah, Saudi Arabia.ORCID https://orcid.org/0000-0002-1329-1391
Saleh AlmatroodiDepartment of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraidah, Saudi Arabia.
Prakash C JoshiDepartment of Zoology and Environmental Sciences, GKV, Haridwar, India.
Mohammad Mahtab AlamDepartment of Basic Medical Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia.
Irfan AhmadDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia.
Gaffar Sarwar ZamanDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia.
Kapil DevDepartment of Biotechnology, Jamia Millia Islamia, New Delhi, India.ORCID https://orcid.org/0000-0002-3995-2370
Department of Biotechnology · INQassim University · SAKing Khalid University · SAAll India Institute of Medical Sciences · INGurukul Kangri Vishwavidyalaya · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer is the most common carcinoma in women worldwide. The present case-control study was aimed to examine the association of BCL-2 (-938C> A), BAX (-248G > A), and HER2 (I655V i.e. A > G) polymorphisms with breast cancer risk in Indian population. This study enrolled 117 breast cancer cases and 104 controls. BCL-2 (-938C > A), BAX (-248G > A), and HER2 Ile655Val polymorphisms were screened by PCR-RFLP method. There was no significance difference in the allelic and genotype frequency of the BCL-2 (-938C > A) and BAX (-248G > A) polymorphisms between cases and controls. In relation to HER2 Ile655Val polymorphism, the statistical analysis of observed genotypic frequencies showed significant association (

Identifiers

PMID33708254
PMCPMC7932784
OpenAlexW3129943497

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.