Evidence map›Paper›PMID 33708246›Full record

ArticleThe journal of venomous animals and toxins including tropical diseases2021

Carmen Sandoval, Gabriela Araujo, Wilfredo Sosa, Sara Avalos, Fernando Silveira, Carlos Corbett, Concepción Zúniga, Marcia Laurenti

Open access · goldAbstract readCase Reports
In one paragraph

Article in The journal of venomous animals and toxins including tropical diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

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  6. Co-infection of Leishmania infantum and a Crithidia-related species in a case of refractory relapsed visceral leishmaniasis with non-ulcerated cutaneous manifestation in Brazil.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Carmen SandovalLaboratory of Infectious Diseases Pathology, Department of Pathology, Medical School (FMUSP), University of São Paulo (USP), São Paulo, SP, Brazil.
Gabriela AraujoLaboratory of Infectious Diseases Pathology, Department of Pathology, Medical School (FMUSP), University of São Paulo (USP), São Paulo, SP, Brazil.
Wilfredo SosaLaboratory of Infectious Diseases Pathology, Department of Pathology, Medical School (FMUSP), University of São Paulo (USP), São Paulo, SP, Brazil.
Sara AvalosMaster Program in Infectious and Zoonotic diseases, School of Microbiology, National Autonomous University of Honduras, Tegucigalpa, Honduras.
Fernando SilveiraDepartment of Parasitology, Evandro Chagas Institute, Secretariat of Health Surveillance, Ministry of Health, Belém, PA, Brazil.
Carlos CorbettLaboratory of Infectious Diseases Pathology, Department of Pathology, Medical School (FMUSP), University of São Paulo (USP), São Paulo, SP, Brazil.
Concepción ZúnigaDepartment of Health Surveillance, School Hospital, Tegucigalpa, Honduras.
Marcia LaurentiLaboratory of Infectious Diseases Pathology, Department of Pathology, Medical School (FMUSP), University of São Paulo (USP), São Paulo, SP, Brazil.ORCID 0000-0002-1080-2440
Universidade de São Paulo · BRInstituto Federal de Educação, Ciência e Tecnologia do Pará · BRNational Autonomous University of Honduras · HNNational Autonomous University of Honduras · HNUniversidad Metropolitana de Honduras · HN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSkin lesions of patients affected by non-ulcerated cutaneous leishmaniasis (NUCL) caused by

methodsTwenty biopsies were processed by immunohistochemistry using primary antibodies to T lymphocytes (CD4, CD8), NK cells, B lymphocytes, macrophages, nitric oxide synthase and interferon-gamma.

resultsImmunohistochemistry revealed higher expression of all cellular types and molecules (IFN-γ, iNOS) in the dermis of diseased skin compared to the skin of healthy individuals (p < 0.05). Morphometric analysis performed in the skin lesions sections showed the predominance of CD8

conclusionOur study improves knowledge of the cellular immune response in non-ulcerated or atypical cutaneous leishmaniasis caused by

Indexed as

Atypical cutaneous leishmaniasisCellular immune responseHondurasImmunohistochemistryLeishmania infantumchagasiNon-ulcerated cutaneous leishmaniasis

Identifiers

PMID33708246
PMCPMC7909480
OpenAlexW3135593189

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.