Evidence map›Paper›PMID 33708216›Full record

ReviewFrontiers in immunology2021

Immunopathogenesis of Craniotomy Infection and Niche-Specific Immune Responses to Biofilm.

Sharon Db de Morais, Gunjan Kak, Joseph P Menousek, Tammy Kielian

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sharon Db de MoraisDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, United States.
Gunjan KakDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, United States.
Joseph P MenousekDepartment of Neurosurgery, University of Nebraska Medical Center, Omaha, NE, United States.
Tammy KielianDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, United States.
University of Nebraska Medical Center · US

Funding

The S. aureus biofilm lifecycleP01AI083211 · NIAID · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI KIELIAN, TAMMY L · 2009 to 2023
$32.1M
Immune mechanisms that promote S. aureus persistence during craniotomy-associated biofilm infectionR01NS107369 · NINDS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI KIELIAN, TAMMY L · 2018 to 2022
$2.1M
NIAID NIH HHS P01 AI083211NINDS NIH HHS R01 NS107369
6 · The paper itself

Abstract

Bacterial infections in the central nervous system (CNS) can be life threatening and often impair neurological function. Biofilm infection is a complication following craniotomy, a neurosurgical procedure that involves the removal and replacement of a skull fragment (bone flap) to access the brain for surgical intervention. The incidence of infection following craniotomy ranges from 1% to 3% with approximately half caused by

Indexed as

BiofilmsImmunity, InnateAnimalsCentral Nervous System Bacterial InfectionsCraniotomyHost-Pathogen InteractionsHumansMyeloid Differentiation Factor 88Staphylococcal InfectionsStaphylococcus aureusSurgical Wound InfectionToll-Like Receptor 2Myeloid Differentiation Factor 88Toll-Like Receptor 2biofilmcraniotomymacrophagemicrogliamyeloid-derived suppressor cellneutrophilStaphylococcus aureus

Identifiers

PMID33708216
PMCPMC7940520
OpenAlexW3129488896

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.