Distribution of fusion transcripts and its clinical impact in patients with acute myeloid leukemia in Sudan.

Abdel Rahim Mahmoud Muddathir, Tarig A M Hamid, Elwaleed M Elamin, Omar F Khabour

Open access · greenAbstract read

In one paragraph

Article in International journal of health sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

0.3field-weighted citation impact, top 45% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

Cytarabine delivered by CD44 and bone targeting redox-sensitive liposomes for treatment of acute myelogenous leukemia.Regenerative biomaterials · 2022
Article
Acute lymphocytic leukemia severity and mortality hospitalizations in the United States: A population-based study.International journal of health sciences
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 3 countries.

Abdel Rahim Mahmoud MuddathirDepartment of Medical Laboratory Technology, Faculty of Applied Medical Sciences, Taibah University, Medina, Kingdom of Saudi Arabia.

Tarig A M HamidDepartment of Hematology and Immunohematology, Sharq Elnile College, Khartoum North, Sudan.

Elwaleed M ElaminDepartment of Histopathology and Molecular Biology, Alzaeim Alazhari University, Khartoum, Sudan.

Omar F KhabourDepartment of Medical Laboratory Sciences, Jordan University of Science and Technology, Irbid, Jordan.

Alzaiem Alazhari University · SDJordan University of Science and Technology · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAcute myeloid leukemia (AML) is a common malignant disorder of hematopoietic progenitor cells that caused by chromosomal translocation and the formation of fusion oncogenes. This study determined the frequencies of fusion genes in Sudanese patients with AML and their clinical impacts.

methodsThis study was conducted at Alzaeim Alazhari University, Khartoum, Sudan. A total of 97 patients with AML were recruited in the study from different clinics in Khartoum state. Quantitative real-time polymerase chain reaction was used to determine types of fusion genes.

resultsThe highest frequency of genetic defects was observed for

conclusionsThe study concluded that

Indexed as

Acute myeloid leukemiaAML1-ETOMLL-AF9real-time polymerase chain reactionSudan

Identifiers

PMID33708041

PMCPMC7934129

OpenAlexW3135655281

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-SA

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.