ArticleAdvanced functional materials2020
Bioprinted Injectable Hierarchically Porous Gelatin Methacryloyl Hydrogel Constructs with Shape-Memory Properties.
Article in Advanced functional materials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.
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The trial behind it
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Who cites it
70 citing papers in PubMed.
- Antifibrotic hydrogel strategies for scarless tissue regeneration: mechanisms, design, and application.Bioactive materials · 2027Review
- Diblock/Triblock Composition Controls Pore Structure and Mechanical Response in Hierarchically Ordered Hydrogels.ACS applied polymer materials · 2026Article
- Green Synthesis of Oat-Derived Carbon Quantum Dot/Gelatin Hydrogel Scaffolds: Enhanced Structural Stability and Bioactivity for Potential Bone Repair.Gels (Basel, Switzerland) · 2026Article
- Coral-inspired immunoreprogramming scaffold reverses the "immune-freeze" microenvironment to promote bone regeneration in steroid-induced osteonecrosis of the femoral head.Bone research · 2026Article
- Apoptotic-mimetic nanovesicles orchestrate immune-vascular-osteogenic crosstalk for critical-sized craniofacial bone regeneration.Materials today. Bio · 2026Article
- Extracellular matrix-mimetic ink for 3D printing and minimally invasive delivery of shape-memory constructs.Materials today. Bio · 2026Article
- Template-Free Wet-Spinning of Multifunctional Sodium Alginate Hollow Hydrogels.Gels (Basel, Switzerland) · 2026Article
- Bioactive photo-crosslinkable hydrogel based on decellularized dental pulp matrix for functional pulp regeneration.BMC oral health · 2026Article
- Microgel-Based Hierarchical Porous Hydrogel Patch with Adhesion and Resilience for Myocardial Infarction.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Multi-scale Engineered Vasculature and Hierarchical Porosity via Volumetric Bioprinting-Guided Photopolymerization-Induced Phase Separation.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Autonomous Hydrogel Actuators Programmed by Endogenous Biochemical Logic for Dual-Stage Morphing and Drug Release.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Advanced cell-adaptable hydrogels for bioprinting.Bioactive materials · 2025Review
- Dual-Ionic Weakly Solvating Electrolyte Design Enables Efficient Fast-Cycling of High-Voltage Anion Shuttle Batteries.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- A comprehensive review of curcumin-based scaffolds in cartilage tissue engineering.Stem cell research & therapy · 2025Review
- Engineered Living Systems Based on Gelatin: Design, Manufacturing, and Applications.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- Microgel-based bioink for extrusion-based 3D bioprinting and its applications in tissue engineering.Bioactive materials · 2025Review
- Integrated biomimetic bioprinting of perichondrium with cartilage for auricle reconstruction.Bioactive materials · 2025Article
- Porous hierarchically ordered hydrogels demonstrating structurally dependent mechanical properties.Nature communications · 2025Article
- Toward Customizable Smart Gels: A Comprehensive Review of Innovative Printing Techniques and Applications.Gels (Basel, Switzerland) · 2025Review
- A Reconfigurable Proangiogenic Hydrogel Patch Enabling Minimally Invasive Drug Delivery.ACS applied materials & interfaces · 2024Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Direct injection of cell-laden hydrogels shows high potentials in tissue regeneration for translational therapy. The traditional cell-laden hydrogels are often used as bulk space fillers to tissue defects after injection, likely limiting their structural controllability. On the other hand, patterned cell-laden hydrogel constructs often necessitate invasive surgical procedures. To overcome these problems, herein, we report a unique strategy for encapsulating living human cells in a pore-forming gelatin methacryloyl (GelMA)-based bioink to ultimately produce injectable hierarchically macro-micro-nanoporous cell-laden GelMA hydrogel constructs through three-dimensional (3D) extrusion bioprinting. The hydrogel constructs can be fabricated into various shapes and sizes that are defect-specific. Due to the hierarchically macro-micro-nanoporous structures, the cell-laden hydrogel constructs can readily recover to their original shapes, and sustain high cell viability, proliferation, spreading, and differentiation after compression and injection. Besides,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.