Evidence map›Paper›PMID 33708029›Full record

ArticleAdvanced functional materials2020

Reversible Functionalization of Clickable Polyacrylamide Gels with Protein and Graft Copolymers.

Hector D Neira, Shaheen Jeeawoody, Amy E Herr

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced functional materials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Hector D NeiraDepartment of Bioengineering, University of California Berkeley Berkeley, CA 94720 (USA).
Shaheen JeeawoodyDepartment of Bioengineering, University of California Berkeley Berkeley, CA 94720 (USA).
Amy E HerrDepartment of Bioengineering, University of California Berkeley Berkeley, CA 94720 (USA).
Berkeley College · US

Funding

UCSF/UCB Joint Graduate Group in BIoengineeringT32GM008155 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DESAI, TEJAL A. · 1985 to 2020
$12.2M
MULTIPLEXED ISOFORM QUANTIFICATION IN HER2-POSITIVE BREAST CANCERR01CA203018 · NCI · UNIVERSITY OF CALIFORNIA BERKELEY · PI HERR, AMY ELIZABETH · 2016 to 2024
$2.8M
Stem Cell Engineering Training ProgramT32GM098218 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI HEALY, KEVIN EDWARD, SCHAFFER, DAVID V · 2011 to 2020
$1.8M
Microfluidic Western Blotting for Targeted Proteomic Analysis of Single Circulating Tumor CellsR21CA183679 · NCI · UNIVERSITY OF CALIFORNIA BERKELEY · PI HERR, AMY ELIZABETH · 2015 to 2017
$634k
NCI NIH HHS R01 CA203018NCI NIH HHS R21 CA183679NIGMS NIH HHS T32 GM008155NIGMS NIH HHS T32 GM098218
6 · The paper itself

Abstract

Modular strategies to fabricate gels with tailorable chemical functionalities are relevant to applications spanning from biomedicine to analytical chemistry. Here, the properties of clickable poly(acrylamide-co-propargyl acrylate) (pAPA) hydrogels are modified via sequential in-gel copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions. Under optimized conditions, each in-gel CuAAC reaction proceeds with rate constants of ~0.003 s

Indexed as

click chemistrydrug deliveryhydrogelsstimuli-responsive materialstissue engineering

Identifiers

PMID33708029
PMCPMC7942169
OpenAlexW3080704208

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.