ArticleInfection and drug resistance2021
Sustained Low Incidence Rates of Central Line-Associated Blood Stream Infections in the Intensive Care Unit.
Article in Infection and drug resistance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prevalence and outcomes of central line-associated bloodstream infections in intensive care units in Saudi Arabia: a systematic review and meta-analysis.Frontiers in microbiology · 2026Pooled it
- Improving central venous catheter care with chlorhexidine gluconate dressings: evidence from a systematic review and Meta-analysis.Journal of health, population, and nutrition · 2024Pooled it
- Device-associated healthcare-associated infections in an intensive care unit in Türkiye: trends and additional costs - a retrospective propensity matched cohort analysis.BMC health services research · 2026Article
- Electronic health record-derived care-exposure burden and central line-associated bloodstream infection among critically ill adults: a multi-source retrospective cohort study.Frontiers in public health · 2026Article
- Bacteremia in the Gulf Cooperation Council Region: A Review of the Literature 2013-2023.Infection and drug resistance · 2025Review
- Distribution and analysis of the resistance profiles of bacteria isolated from blood cultures in the intensive care unit.Frontiers in microbiology · 2025Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCentral line-associated bloodstream infection (CLABSI) is an important cause of increased morbidity and mortality in ICUs. The occurrence of CLABSI in significantly higher in developing countries and contributes to the burden of healthcare-associated infections.
methodsThis prospective study was carried out from January 2016 to December 2019 in the intensive care unit at King Faisal Medical Complex in Taif, Saudi Arabia. The Society for Healthcare Epidemiology of America/Infectious Diseases Society of America (SHEA/IDSA) recommendations were introduced and implemented during 2017-2019. In the post-intervention period, observation of hand hygiene, CLABSI bundle compliance, and benchmarking of CLABSI rates were carried out.
resultsThe CLABSI incidence rate was 1.12/1,000 central-line days, with a 0.51 utilization ratio in the pre-intervention period. This dropped to 0.46/1,000 central line days with a 0.44 utilization ratio in the post-intervention period. This reduction was also confirmed in benchmarking with National Healthcare Safety Network (NHSN) (50th-75th) percentile pre-intervention vs (25th-50th) percentile post-intervention. Institutional risk assessment revealed a formal educational program as a potential need for improvement. The CLABSIs were caused predominantly by multidrug-resistant
conclusionWe observed a reduction and sustained low incidence rate of CLABSI benchmarking to NHSN for 3 years after implementation of the basic SHEA/IDSA recommendations.
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