Observational studyScientific reports2021
Obstructive sleep apnea is associated with impaired renal function in patients with diabetic kidney disease.
Observational study in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- The impact of sleep disturbances in individuals with comorbid diabetes and chronic kidney disease: a systematic review.Sleep & breathing = Schlaf & Atmung · 2025Pooled it
- Obstructive sleep apnoea is associated with accelerated progression of diabetic kidney disease.Diabetic medicine : a journal of the British Diabetic Association · 2026Article
- Multimodal Magnetic Resonance Imaging in Diabetic Kidney Disease: From Pathophysiological Insights to Clinical Applications.Diagnostics (Basel, Switzerland) · 2026Review
- Identification of risk factors and development of a predictive model for early renal impairment in patients with obstructive sleep apnea-hypopnea syndrome.BMC pulmonary medicine · 2026Article
- Impact of continuous positive airway pressure therapy on metabolic and renal parameters in patients with obstructive sleep apnea, type 2 diabetes mellitus, and chronic kidney disease: a prospective cohort study.International urology and nephrology · 2026Article
- Exploring the cardiometabolic profile of Emirati adults at risk for obstructive sleep apnea: findings from the UAE healthy future study.Frontiers in sleep · 2026Article
- Knowledge, Attitudes, and Practices Regarding Hyperuricemia and Sleep Among Patients: A Cross-Sectional Study.Patient preference and adherence · 2026Article
- Chronic lung diseases and kidney disease: pathophysiology and management.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025Review
- Obstructive sleep apnea in type 2 diabetes: prevalence and limitations of the Berlin questionnaire and Epworth sleepiness scale in identifying high-risk patients.Sleep & breathing = Schlaf & Atmung · 2025Article
- Association between sleep duration and estimated glomerular filtration rate in Chinese patients with diabetes: evidence from a cross-sectional study.European journal of medical research · 2025Observational
- Correlation analysis between hemoglobin and type 2 diabetic nephropathy: a two-center retrospective study.Acta diabetologica · 2025Article
- A Structured Narrative Review of the OSA-T2DM Axis.Journal of clinical medicine · 2025Review
- Nonlinear association between blood urea nitrogen to creatinine ratio and obstructive sleep apnea: a cross-sectional study from NHANES.BMC pulmonary medicine · 2025Article
- Clinically available predictors of obstructive sleep apnoea requiring treatment in type 2 diabetes patients in primary care.Scientific reports · 2025Article
- Exploring Bidirectional Causality between Obstructive Sleep Apnea and Chronic Kidney Disease via Mendelian Randomization.Nature and science of sleep · 2025Article
- Causal association between sleep traits and diabetic nephropathy.Archives of medical science : AMS · 2025Article
- Approach the Patient With Obstructive Sleep Apnea and Obesity.The Journal of clinical endocrinology and metabolism · 2024Article
- Commentary: Obstructive sleep apnea in the hemodialysis population: are clinicians putting existing scientific evidence into practice?Frontiers in nephrology · 2024Article
- Causal effects of obstructive sleep apnea on chronic kidney disease and renal function: a bidirectional Mendelian randomization study.Frontiers in neurology · 2024Article
- Female obesity: clinical and psychological assessment toward the best treatment.Frontiers in endocrinology · 2024Review
Corrections and comments
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Authors and funding
15 authors at 9 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obstructive sleep apnea (OSA) is a recognized risk factor for the development of diabetic kidney disease (DKD). Our objectives were to compare the urinary albumin-creatinine ratio (UACR) and estimated glomerular filtration rate (eGFR) of patients with DKD according to OSA severity, and to evaluate the contribution of sleep parameters to their renal function. In a multicenter, observational, cross-sectional study, 214 patients with DKD were recruited. After a sleep study, UACR and eGFR were measured, as well as serum creatinine, fasting glucose, glycated hemoglobin, insulin resistance, lipid profile and C-reactive protein. UACR was higher in severe OSA patients (920 ± 1053 mg/g) than in moderate (195 ± 232 mg/g, p < 0.001) or mild OSA/non-OSA subjects (119 ± 186 mg/g, p < 0.001). At the same time, eGFR showed an OSA severity-dependent reduction (48 ± 23 vs. 59 ± 21 vs. 73 ± 19 ml/min per 1.73 m
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