Evidence map›Paper›PMID 33707589›Full record

ArticleScientific reports2021

Hospital-diagnosed infections with Escherichia coli clonal group ST131 are mostly acquired in the community.

Allison Muller, Houssein Gbaguidi-Haore, Pascal Cholley, Didier Hocquet, Marlène Sauget, Xavier Bertrand

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Escherichia coli ST131 Drives Carbapenem Use for E. coli Bloodstream Infections.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Emergence ofMicrobiology spectrum · 2025
    Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Predominance ofMedicina (Kaunas, Lithuania) · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Genotypic Characteristics and Antimicrobial Resistance ofAntibiotics (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Allison MullerHygiène Hospitalière, Centre Hospitalier Universitaire, 3 Boulevard Fleming, 25030, Besançon, Cedex, France.
Houssein Gbaguidi-HaoreHygiène Hospitalière, Centre Hospitalier Universitaire, 3 Boulevard Fleming, 25030, Besançon, Cedex, France.
Pascal CholleyHygiène Hospitalière, Centre Hospitalier Universitaire, 3 Boulevard Fleming, 25030, Besançon, Cedex, France.
Didier HocquetHygiène Hospitalière, Centre Hospitalier Universitaire, 3 Boulevard Fleming, 25030, Besançon, Cedex, France.
Marlène SaugetHygiène Hospitalière, Centre Hospitalier Universitaire, 3 Boulevard Fleming, 25030, Besançon, Cedex, France. msauget@chu-besancon.fr.
Xavier BertrandHygiène Hospitalière, Centre Hospitalier Universitaire, 3 Boulevard Fleming, 25030, Besançon, Cedex, France.
Centre National de la Recherche Scientifique · FRCentre Hospitalier Universitaire de Besançon · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The worldwide spread of E. coli ST131 has significantly contributed to the dissemination of E. coli producing extended-spectrum β-lactamases (ESBL). In a French University hospital, we assessed the molecular features of ESBL-producing E. coli and identified risk factors in patients for colonization or infection with E. coli ST131. Over a 2-year period (2015-2017), each patient with at least one clinical isolate or one screening isolate positive with ESBL-producing E. coli were included (n = 491). The ST131 clonal group accounted for 17.5% (n = 86) of all ESBL-producing E. coli and represented 57.3% isolates of phylogroup B2. FimH-based sub-typing showed that 79.1% (68/86) of ST131 isolates were fimH30, among which 67.6% (n = 46), 20.6% (n = 14) and 11.8% (n = 8) isolates harbored genes encoding the ESBL CTX-M-15, CTX-M-27, and CTX-M-14, respectively. The multivariate analysis identified two factors independently associated with ST131 ESBL-producing E. coli isolates: infection (Odds ratio [OR] = 1.887, 95% confidence interval [CI]: 1.143-3.115; p = 0.013) and community acquisition (OR = 2.220, 95% CI: 1.335-3.693; p = 0.002). In conclusion, our study confirmed the predominance of ST131 clonal group among ESBL-producing E. coli and the difficulty to identify common risk factors associated with carriage of this pandemic clonal group.

Indexed as

beta-LactamasesCarrier StateClone CellsCommunity-Acquired InfectionsCross InfectionEscherichia coliEscherichia coli InfectionsHumansMultivariate AnalysisPhylogenyRisk Factorsbeta-Lactamases

Identifiers

PMID33707589
PMCPMC7952690
OpenAlexW3133975350

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.