Trial reportScientific reports2021
The effects of a music intervention during port catheter placement on anxiety and stress.
Trial report in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Acoustic stimulation for relieving pain during venipuncture: a systematic review and network meta-analysis.BMJ open · 2023Pooled it
- Effectiveness of an interactive music tablet intervention to reduce procedural anxiety in children: a randomized controlled trial.Scientific reports · 2026Trial
- The effects of music and virtual reality on pain and anxiety during central venous port implantation: a randomised clinical trial.Scientific reports · 2026Trial
- Effects of music therapy as an alternative treatment on depression in children and adolescents with ADHD by activating serotonin and improving stress coping ability.BMC complementary medicine and therapies · 2023Trial
- Music Listening in Medicine and Healthcare: A Scoping Review.Healthcare (Basel, Switzerland) · 2026Review
- Is There a Role for Music Intervention in Reducing Anxiety and Pain in Males During Outpatient Flexible Cystoscopy? A Randomized Controlled Study.Urology research & practice · 2025Article
- Virtual Reality and Sound Intervention under Chemotherapy (ViSu): study protocol for a three-arm randomised-controlled trial.BMJ open · 2025Article
- Preoperative Anxiety Impact on Anesthetic and Analgesic Use.Medicina (Kaunas, Lithuania) · 2023Review
- "This Won't Hurt a Bit": Is There a Role for Music in Bedside Procedures?Critical care explorations · 2023Article
- COVID-19, diabetes mellitus type 2, endocrine genetics, and pituitary and adrenal diseases.Hormones (Athens, Greece) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Studies have shown that perioperative music interventions can reduce patients' anxiety levels. However, in small operations like port catheter surgery evidence is sparse. The present single-blinded, randomised controlled two-armed study included 84 female patients undergoing port catheter placement who were randomly assigned to either listening to music during surgery vs. no music intervention. The medical staff was blind to group allocation. On the day of the surgery anxiety and stress levels were evaluated using subjective (STAI questionnaire, visual analogue scales) and objective (vital parameters, salivary cortisol) parameters at different time points (before the surgery, at the end of the surgery and 1 h post-surgery). The music group showed significant reductions of systolic blood pressure (from 136.5 mmHg ± 26.1 to 123.3 mmHg ± 22.0, p = .002) and heart rate (from 75.6 bpm ± 12.3 to 73.1 bpm ± 12.2, p = .035) from beginning of the surgery to skin suture, whereas the control group did not. No significant effects of the music intervention on subjective anxiety measures or salivary cortisol were revealed. In sum, the study demonstrates that a music intervention during port catheter placement positively influences physiological anxiety levels, whereas no effects were revealed for subjective anxiety and salivary cortisol. Thus, music can be considered as a low cost addition in clinical routine in order to reduce patients' heart rate and blood pressure. Future studies are encouraged to further explore the differential effects of intraoperative music interventions on physiological, endocrinological and subjective anxiety levels.
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