ArticleScientific reports2021
Microbicidal actives with virucidal efficacy against SARS-CoV-2 and other beta- and alpha-coronaviruses and implications for future emerging coronaviruses and other enveloped viruses.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Disinfection methods against SARS-CoV-2: a systematic review.The Journal of hospital infection · 2022Pooled it
- Virucidal Efficacy of Organic Acids and Plant Essential Oils.Food and environmental virology · 2025Article
- Dynamics of respiratory virus spread indoors suggest a holistic approach for exposure risk mitigation.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- Soap and water cleaning versus bleach-based cleaners for eliminating SARS-CoV-2 infection.Journal of public health in Africa · 2025Review
- Virucidal activity of porphyrin-based metal-organic frameworks against highly pathogenic coronaviruses and hepatitis C virus.Materials today. Bio · 2024Article
- Mechanisms of action of microbicides commonly used in infection prevention and control.Microbiology and molecular biology reviews : MMBR · 2024Review
- Antiviral Natural Products, Their Mechanisms of Action and Potential Applications as Sanitizers and Disinfectants.Food and environmental virology · 2023Review
- Development and efficacy assessment of hand sanitizers and polylactic acid films incorporating caffeic acid and vanillin for enhanced antiviral properties against HCoV-229E.Virology journal · 2023Article
- The Effect of Water Hardness and pH on the Efficacy of Peracetic Acid and Sodium Hypochlorite against SARS-CoV-2 on Food-Contact Surfaces.Foods (Basel, Switzerland) · 2023Article
- Efficacy of Peracetic Acid and Sodium Hypochlorite against SARS-CoV-2 on Contaminated Surfaces.Applied and environmental microbiology · 2023Article
- Virus Inactivation Based on Optimal Surfactant Reservoir of Mesoporous Silica.ACS applied bio materials · 2023Article
- Quaternary ammonium compounds of emerging concern: Classification, occurrence, fate, toxicity and antimicrobial resistance.Journal of hazardous materials · 2023Review
- Review
- Disinfection and decontamination in the context of SARS-CoV-2-specific data.Journal of medical virology · 2022Review
- Application of an Ultrasonic Nebulizer Closet in the Disinfection of Textiles and Footwear.International journal of environmental research and public health · 2022Article
- Disinfectants against SARS-CoV-2: A Review.Viruses · 2022Review
- Evaluation and comparison of three virucidal agents on inactivation of Nipah virus.Scientific reports · 2022Article
- Emerging SARS-CoV-2 Mutational Variants of Concern Should Not Vary in Susceptibility to Microbicidal Actives.Life (Basel, Switzerland) · 2022Article
- Inactivation of SARS-CoV-2 by a chitosan/α-AgScientific reports · 2022Article
- Indirect transmission of severe acute respiratory syndrome coronavirus virus 2 (SARS-CoV-2): What do we know and what do we not know?Infection control and hospital epidemiology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mitigating the risk of acquiring coronaviruses including SARS-CoV-2 requires awareness of the survival of virus on high-touch environmental surfaces (HITES) and skin, and frequent use of targeted microbicides with demonstrated efficacy. The data on stability of infectious SARS-CoV-2 on surfaces and in suspension have been put into perspective, as these inform the need for hygiene. We evaluated the efficacies of formulated microbicidal actives against alpha- and beta-coronaviruses, including SARS-CoV-2. The coronaviruses SARS-CoV, SARS-CoV-2, human coronavirus 229E, murine hepatitis virus-1, or MERS-CoV were deposited on prototypic HITES or spiked into liquid matrices along with organic soil loads. Alcohol-, quaternary ammonium compound-, hydrochloric acid-, organic acid-, p-chloro-m-xylenol-, and sodium hypochlorite-based microbicidal formulations were evaluated per ASTM International and EN standard methodologies. All evaluated formulated microbicides inactivated SARS-CoV-2 and other coronaviruses in suspension or on prototypic HITES. Virucidal efficacies (≥ 3 to ≥ 6 log
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.