Evidence map›Paper›PMID 33707451›Full record

Observational studyScientific reports2021

The effect of ABO blood group and antibody class on the risk of COVID-19 infection and severity of clinical outcomes.

Marwa Ali Almadhi, Abdulkarim Abdulrahman, Abdulla Alawadhi, Ali A Rabaan, Stephen Atkin, Manaf AlQahtani

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Vitamin D status and blood group among severe COVID-19 patients.Annals of medicine and surgery (2012) · 2023
    Article
  7. Article
  8. Blood-Type-A is a COVID-19 infection and hospitalization risk in a Turkish cohort.Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine · 2023
    Article
  9. Article
  10. Review
  11. Observational
  12. Article
  13. Article
  14. Host polymorphisms and COVID-19 infection.Advances in clinical chemistry · 2022
    Article
  15. ABO blood grouping and COVID-19: a hospital-based study in Eastern India.The Egyptian journal of medical human genetics · 2022
    Article
  16. The association of ABO blood group with the asymptomatic COVID-19 cases in India.Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis · 2021
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Marwa Ali AlmadhiNational Taskforce for Combating the Coronavirus (COVID-19), Riffa, Bahrain.
Abdulkarim AbdulrahmanNational Taskforce for Combating the Coronavirus (COVID-19), Riffa, Bahrain.
Abdulla AlawadhiNational Taskforce for Combating the Coronavirus (COVID-19), Riffa, Bahrain.
Ali A RabaanMolecular Diagnostic Laboratory, John Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.
Stephen AtkinRoyal College of Surgeons in Ireland, Busaiteen, Bahrain.
Manaf AlQahtaniNational Taskforce for Combating the Coronavirus (COVID-19), Riffa, Bahrain. drmanaf@gmail.com.
Bahrain Center for Strategic International and Energy Studies · BHRoyal College of Surgeons in Ireland - Bahrain · BHSaudi Aramco Medical Services Organization · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic has affected more than 100 million cases and caused immense burdens on governments and healthcare systems worldwide. Since its emergence in December 2019, research has been focused on treating the infected, identifying those at risk and preventing spread. There is currently no known biological biomarker that predicts the risk of infection. Several studies emerged suggesting an association between ABO blood group and the risk of COVID-19 infection. In this study, we used retrospective observational data in Bahrain to investigate the association between ABO blood group and risk of infection, as well as susceptibility to severe ICU-requiring infection. We found a higher risk associated with blood group B, and a lower risk with blood group AB. No association was observed between blood group and the risk of a severe ICU-requiring infection. We extended the analysis to study the association by antibodies; anti-a (blood groups B and O) and anti-b (blood groups A and O). No association between antibodies and both risk of infection or susceptibility to severe infection was found. The current study, along with the variation in blood group association results, indicates that blood group may not be an ideal biomarker to predict risk of COVID-19 infection.

Indexed as

ABO Blood-Group SystemCOVID-19Critical CareCross-Sectional StudiesHumansABO Blood-Group System

Identifiers

PMID33707451
PMCPMC7952683
OpenAlexW3133555554

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.