Evidence map›Paper›PMID 33707388›Full record

ArticleThe Indian journal of medical research2020

Indian Council of Medical Research consensus document on hepatocellular carcinoma.

Bhawna Sirohi, Shailesh V Shrikhande, Vinay Gaikwad, Amol Patel, Shraddha Patkar, Mahesh Goel, Munita Bal, Atul Sharma, Raj Kumar Shrimali, Vikram Bhatia and 6 more

Abstract readConsensus Statement
In one paragraph

Article in The Indian journal of medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. The changing epidemiology of hepatocellular carcinoma!Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2023
    Article
  4. Multi-center prospective survey of hepatocellular carcinoma in Kerala: More than 1,200 cases.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2023
    Article
  5. Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Bhawna SirohiDepartment of Medical Oncology, Apollo Proton Cancer Centre, Chennai, India.
Shailesh V ShrikhandeDepartment of Gastrointestinal & Hepato-Pancreato-biliary Service, Tata Memorial Centre, Mumbai, Maharashtra, India.
Vinay GaikwadDepartment of Gastrointestinal & Hepato-Pancreato-biliary Service, Paras Hospital, Gurugram, Haryana, India.
Amol PatelDepartment of Medical Oncology, Army Hospital Research & Referral, New Delhi, India.
Shraddha PatkarDepartment of Gastrointestinal & Hepato-Pancreato-biliary Service, Tata Memorial Centre, Mumbai, Maharashtra, India.
Mahesh GoelDepartment of Gastrointestinal & Hepato-Pancreato-biliary Service, Tata Memorial Centre, Mumbai, Maharashtra, India.
Munita BalDepartment of Pathology, Tata Memorial Centre, Mumbai, Maharashtra, India.
Atul SharmaDepartment of Medical Oncology, Dr. B.R.A Institute-Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India.
Raj Kumar ShrimaliDepartment of Radiation Oncology, Tata Medical Centre, Kolkata, West Bengal, India.
Vikram BhatiaDepartment of Gastroenterology, Institute of Liver & Biliary Sciences, New Delhi, India.
Suyash KulkarniDepartment of Interventional Radiology, Tata Memorial Centre, Mumbai, Maharashtra, India.
Deep Narayan SrivastavaDepartment of Radiodiagnosis, Dr. B.R.A Institute-Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India.
Tanvir KaurDivision of Non-Communicable Diseases, Indian Council of Medical Research, New Delhi, India.
R S DhaliwalDivision of Non-Communicable Diseases, Indian Council of Medical Research, New Delhi, India.
Goura Kishor RathDepartment of Radiation Oncology, Dr. B.R.A Institute-Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India.
Indian Council of Medical Research Guidelines Working Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This document aims to assist oncologists in making clinical decisions encountered while managing their patients with hepatocellular carcinoma (HCC), specific to Indian practice, based on consensus among experts. Most patients are staged by Barcelona Clinic Liver Cancer (BCLC) staging system which comprises patient performance status, Child-Pugh status, number and size of nodules, portal vein invasion and metastasis. Patients should receive multidisciplinary care. Surgical resection and transplant forms the mainstay of curative treatment. Ablative techniques are used for small tumours (<3 cm) in patients who are not candidates for surgical resection (Child B and C). Patients with advanced (HCC should be assessed on an individual basis to determine whether targeted therapy, interventional radiology procedures or best supportive care should be provided. In advanced HCC, immunotherapy, newer targeted therapies and modern radiation therapy have shown promising results. Patients should be offered regular surveillance after completion of curative resection or treatment of advanced disease.

Indexed as

Biomedical ResearchCarcinoma, HepatocellularLiver NeoplasmsHumansNeoplasm StagingGuidelineshepatocellular carcinomaIndian Council of Medical Researchmanagement

Identifiers

PMID33707388
PMCPMC8157895

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.