ArticleOpen heart2021
Prevalence and determinants of hypertension control among almost 100 000 treated adults in the UK.
Article in Open heart, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 2 of them syntheses that pooled it.
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Who cites it
53 citing papers in PubMed, 2 syntheses or guidelines pooled it, 83 citations in OpenAlex.
- Evening versus morning dosing regimen drug therapy for hypertension.The Cochrane database of systematic reviews · 2024Pooled it
- Disparities in Prevalence and Barriers to Hypertension Control: A Systematic Review.International journal of environmental research and public health · 2022Pooled it
- Trial
- Cardiovascular outcomes in adults with hypertension with evening versus morning dosing of usual antihypertensives in the UK (TIME study): a prospective, randomised, open-label, blinded-endpoint clinical trial.Lancet (London, England) · 2022Trial
- Antihypertensive Medication Patterns in Patients with Hypertension that is Harder to Control: Insights from the EnligHTN Study.Advances in therapy · 2026Article
- Extreme Heat Exposure and Blood Pressure in Community Health Center Patients.JAMA network open · 2026Article
- Development and validation of a hypertension risk prediction model using electronic health records data from general practices in Hampshire and Isle of Wight integrated care system.BMC cardiovascular disorders · 2026Article
- Recognition, treatment, and control of hypertension in the Danish population-based Lolland-Falster Health Study.European journal of public health · 2026Article
- The future and digital transformation of hypertension care: results from the ESH CARE app trial.European journal of preventive cardiology · 2026Article
- Factors impacting poor hypertension control in young urban adults in a Malaysian primary care clinic.BMC primary care · 2026Article
- Article
- Circulating inflammatory proteins predict dementia risk, and are linked to structural brain changes and modifiable risk factors.Alzheimer's research & therapy · 2026Article
- Hypertension prevalence, detection, treatment and control among 1.4 million adults in England: a cross-sectional analysis from the Our Future Health study in 2022-2025.BMJ public health · 2026Article
- Implications of the 2025 AHA/ACC hypertension guideline on hypertension prevalence, treatment eligibility and blood pressure control in Nigeria: a cross-sectional comparative study.BMJ public health · 2026Article
- Blood Pressure and Hypertension Among Adults Aged 80 and Above: Findings From the Population-Based German Health Survey Gesundheit 65.International journal of hypertension · 2026Article
- Effect of dietary fiber intake on blood pressure control in type 2 diabetic patients in selected hospitals of Ethiopia.Scientific reports · 2025Article
- Phenotypes of Hypertension: Impact of Age and Sex on Hemodynamic Mechanisms.Journal of the American Heart Association · 2025Article
- Sex-specific formulations of doxazosin mesylate via direct powder extrusion 3D printing.Drug delivery and translational research · 2025Article
- Hypertension Control Rate, Associated Factors, Facilitators, and Barriers in Kerala, India: A Mixed-Methods Study.Cureus · 2025Article
- Investigating the non-linear association between sleep duration and type 2 diabetes: conventional and Mendelian randomization analyses from the UK Biobank.Journal of diabetes investigation · 2025Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 2 countries.
Funding
Abstract
objectiveTo identify factors associated with hypertension control among treated middle-aged UK adults.
methodsA cross-sectional population-based study including 99 468 previously diagnosed, treated hypertensives enrolled in the UK Biobank. Hypertension control was defined as systolic blood pressure <140 mm Hg and diastolic blood pressure <90 mm Hg.
resultsMedian age was 62.3 years (IQR 57.3 to 66.0), 45.9% female, 92.0% white, 40.1% obese, 9.3% current smokers and 19.4% had prior cardiovascular disease. 38.1% (95% CI 37.8% to 38.4%) were controlled. In multivariable logistic regression, associations with lack of hypertension control included: older age (OR 0.61, 95% CI 0.58 to 0.64 for 60-69 years compared with age 40-50 years), higher alcohol use (OR 0.61, 95% CI 0.58 to 0.64, for consuming >30 units per week compared with none), black ethnicity (OR 0.73, 95% CI 0.65 to 0.82 compared with white), obesity (OR 0.73, 95% CI 0.71 to 0.76 compared with normal body mass index). The strongest positive association with control was having ≥3 comorbidities (OR 2.09, 95% CI 1.95 to 2.23). Comorbidities associated with control included cardiovascular disease (OR 2.11, 95% CI 2.04 to 2.19), migraines (OR 1.68, 95% CI 1.56 to 1.81), diabetes (OR 1.32, 95% CI 1.27 to 1.36) and depression (OR 1.27, 95% CI 1.20 to 1.34).
conclusionsIn one of the largest population-based analyses of middle-aged adults with measured blood pressure, the majority of treated hypertensives were uncontrolled. Risk factors for hypertension were associated with a lower probability of control. Having a comorbidity was associated with higher probability of control, possibly due to more frequent interaction with the healthcare system and/or appropriate management of those at greater cardiovascular risk.
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