Evidence map›Paper›PMID 33707205›Full record

RevieweNeuro

Vertebrate Evolution Conserves Hindbrain Circuits despite Diverse Feeding and Breathing Modes.

Shun Li, Fan Wang

Open access · goldAbstract readReview
In one paragraph

Review in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Feeding biomechanics in vertebrates and beyond.Anatomical record (Hoboken, N.J. : 2007) · 2026
    Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Shun LiDepartment of Neurobiology, Duke University, Durham, NC 27710.ORCID 0000-0002-8580-3843
Fan WangDepartment of Neurobiology, Duke University, Durham, NC 27710 fan_wang@mit.edu.ORCID 0000-0003-2988-0614
Duke University · US

Funding

Theory and Modeling of the Orofacial Active SensationU19NS107466 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MITRA, PARTHA PRATIM · 2018 to 2022
$14.9M
NINDS NIH HHS U19 NS107466
6 · The paper itself

Abstract

Feeding and breathing are two functions vital to the survival of all vertebrate species. Throughout the evolution, vertebrates living in different environments have evolved drastically different modes of feeding and breathing through using diversified orofacial and pharyngeal (oropharyngeal) muscles. The oropharyngeal structures are controlled by hindbrain neural circuits. The developing hindbrain shares strikingly conserved organizations and gene expression patterns across vertebrates, thus begs the question of how a highly conserved hindbrain generates circuits subserving diverse feeding/breathing patterns. In this review, we summarize major modes of feeding and breathing and principles underlying their coordination in many vertebrate species. We provide a hypothesis for the existence of a common hindbrain circuit at the phylotypic embryonic stage controlling oropharyngeal movements that is shared across vertebrate species; and reconfiguration and repurposing of this conserved circuit give rise to more complex behaviors in adult higher vertebrates.

Indexed as

RhombencephalonVertebratesAnimalsBiological Evolutionbreathingcentral rhythm generatorevolutionfeedinghindbrain

Identifiers

PMID33707205
PMCPMC8174041
OpenAlexW3135115252

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.