ArticleWorld journal of surgical oncology2021
The clinical significance of preoperative plasma fibrinogen levels and platelet counts in resectable colon cancer.
Article in World journal of surgical oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Article
- Predictors of early colorectal cancer metastasis to lymph nodes: providing rationale for therapy decisions.Frontiers in oncology · 2024Review
- Systematic oxidative stress indices predicts prognosis in patients with urothelial carcinoma of the upper urinary tract after radical nephroureterectomy.European journal of medical research · 2023Article
- A novel potential inflammation-nutrition biomarker for predicting lymph node metastasis in clinically node-negative colon cancer.Frontiers in oncology · 2023Article
- Fibrinogen levels in relation to colorectal cancer onset: A nested case-cohort study from the Moli-sani cohort.Frontiers in cardiovascular medicine · 2022Article
- Prognostic Impact of Platelet-Large Cell Ratio In Myelodysplastic Syndromes.Frontiers in oncology · 2022Article
- Fibrinogen/albumin ratio index is an independent predictor of recurrence-free survival in patients with intrahepatic cholangiocarcinoma following surgical resection.World journal of surgical oncology · 2021Article
- Nomogram to predict postoperative infectious complications after surgery for colorectal cancer: a retrospective cohort study in China.World journal of surgical oncology · 2021Article
- Preoperative plasma D-dimer independently predicts survival in patients with pancreatic ductal adenocarcinoma undergoing radical resection.World journal of surgical oncology · 2021Article
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2 authors.
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Abstract
BACKGROUND AND
aimSeveral aspects of the correlation between colon cancer and hemostatic markers are still unknown to many researchers in the field. In this study, we evaluated the association, if any, of preoperative platelet (PLT) counts and plasma fibrinogen levels with postoperative lymph node involvement and venous invasion in colon cancer patients.
methodsThis study retrospectively included eighty patients with colon cancer (mean age 58.09 years; 37% female 63% male).
resultsPatients with negative lymph nodes and venous invasion showed a significantly lower PLT count and higher fibrinogen level than their counterparts, i.e., patients with positive lymph nodes (p<0.001, all of them) and venous invasion (p<0.001, all of them). The results also showed a positive association of PLT counts and fibrinogen levels with lymphatic invasion (r=0.670, p<0.001 and r=0.639, p<0.001, respectively) and a positive association of PLT counts and fibrinogen levels with venous invasion (r=0.3988, p<0.001 and r=0.5268, p<0.001, respectively). According to the results of the ROC curve analysis, when the PLT count cutoff was 290/mm
conclusionThe preoperative PLT count and plasma fibrinogen level may be considered key markers to monitor postoperative lymph node involvement and venous invasion in colon cancer patients.
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