Evidence map›Paper›PMID 33706764›Full record

ArticleBMC medicine2021

Reducing youth suicide: systems modelling and simulation to guide targeted investments across the determinants.

Jo-An Occhipinti, Adam Skinner, Frank Iorfino, Kenny Lawson, Julie Sturgess, Warren Burgess, Tracey Davenport, Danica Hudson, Ian Hickie

Open access · goldAbstract read
In one paragraph

Article in BMC medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 72 citations in OpenAlex.

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  9. Beyond capacity limits: can social cohesion offset the impact of service constraints on youth mental health?European psychiatry : the journal of the Association of European Psychiatrists · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Jo-An Occhipinti *Brain and Mind Centre, Faculty of Medicine and Health, University of Sydney, Camperdown, Australia. jo-an.occhipinti@sydney.edu.au.ORCID 0000-0002-2380-1092
Adam Skinner *Brain and Mind Centre, Faculty of Medicine and Health, University of Sydney, Camperdown, Australia.
Frank IorfinoBrain and Mind Centre, Faculty of Medicine and Health, University of Sydney, Camperdown, Australia.
Kenny LawsonTranslational Health Research Institute, Western Sydney University, Penrith, Australia.
Julie SturgessNorth Coast Primary Health Network, Ballina, Australia.
Warren BurgessNorth Coast Primary Health Network, Ballina, Australia.
Tracey DavenportBrain and Mind Centre, Faculty of Medicine and Health, University of Sydney, Camperdown, Australia.
Danica HudsonNorth Coast Primary Health Network, Ballina, Australia.
Ian HickieBrain and Mind Centre, Faculty of Medicine and Health, University of Sydney, Camperdown, Australia.
The University of Sydney · AUTranslational Research Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundReducing suicidal behaviour (SB) is a critical public health issue globally. The complex interplay of social determinants, service system factors, population demographics, and behavioural dynamics makes it extraordinarily difficult for decision makers to determine the nature and balance of investments required to have the greatest impacts on SB. Real-world experimentation to establish the optimal targeting, timing, scale, frequency, and intensity of investments required across the determinants is unfeasible. Therefore, this study harnesses systems modelling and simulation to guide population-level decision making that represent best strategic allocation of limited resources.

methodsUsing a participatory approach, and informed by a range of national, state, and local datasets, a system dynamics model was developed, tested, and validated for a regional population catchment. The model incorporated defined pathways from social determinants of mental health to psychological distress, mental health care, and SB. Intervention scenarios were investigated to forecast their impact on SB over a 20-year period.

resultsA combination of social connectedness programs, technology-enabled coordinated care, post-attempt assertive aftercare, reductions in childhood adversity, and increasing youth employment projected the greatest impacts on SB, particularly in a youth population, reducing self-harm hospitalisations (suicide attempts) by 28.5% (95% interval 26.3-30.8%) and suicide deaths by 29.3% (95% interval 27.1-31.5%). Introducing additional interventions beyond the best performing suite of interventions produced only marginal improvement in population level impacts, highlighting that 'more is not necessarily better.'

conclusionResults indicate that targeted investments in addressing the social determinants and in mental health services provides the best opportunity to reduce SB and suicide. Systems modelling and simulation offers a robust approach to leveraging best available research, data, and expert knowledge in a way that helps decision makers respond to the unique characteristics and drivers of SB in their catchments and more effectively focus limited health resources.

Indexed as

Decision Support TechniquesSuicide PreventionSystems AnalysisComputer SimulationHumansDecision analysisSimulationStrategic planningSuicide preventionSystems modelling

Identifiers

PMID33706764
PMCPMC7952221
OpenAlexW3134987741

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.