ArticleBMC medicine2021
Reducing youth suicide: systems modelling and simulation to guide targeted investments across the determinants.
Article in BMC medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- Participatory systems mapping: a review of population health research practice.Health research policy and systems · 2026Pooled it
- System dynamics modelling methods for public health policy evaluation: a systematic literature review focussing on mental health and substance use disorders.BMC public health · 2026Pooled it
- Participatory systems modelling to improve mental health systems in Bogotá, Colombia: stakeholders' perspectives, experiences and networks.International journal of mental health systems · 2026Article
- The involvement of stakeholders in computational model development to support decision-making in public health: a scoping review.BMC public health · 2025Article
- Trends and dynamics of homelessness in Hong Kong: evidence from population survey in 2015 and 2021.BMC public health · 2025Article
- Understanding Contagion of Suicidal Ideation: The Importance of Taking Into Account Social and Structural Determinants of Health.Mental health science · 2025Article
- Examining the Impact of Youth Mental Health Services Capacity Growth Trajectories and Digital Interventions on Youth Mental Health Outcomes: System Dynamics Modeling Analysis.Journal of medical Internet research · 2025Article
- An evaluation of the feasibility, value and impact of using participatory modelling to inform the development of a regional system dynamics model for youth suicide prevention.Health research policy and systems · 2025Article
- Beyond capacity limits: can social cohesion offset the impact of service constraints on youth mental health?European psychiatry : the journal of the Association of European Psychiatrists · 2025Article
- Social Determinants and Developmental Factors Influencing Suicide Risk and Self-Injury in Healthcare Contexts.International journal of environmental research and public health · 2025Article
- Modelling the impact of environmental and social determinants on mental health using generative agents.NPJ digital medicine · 2025Review
- Analysis of how a complex systems perspective is applied in studies on socioeconomic inequalities in health and health behaviour-a call for reporting guidelines.Health research policy and systems · 2024Article
- Incorporating Complexity and System Dynamics into Economic Modelling for Mental Health Policy and Planning.PharmacoEconomics · 2024Article
- Participatory systems modelling to inform improvements in the social and emotional wellbeing of young Aboriginal and Torres Strait Islander people in Australia.The Lancet regional health. Western Pacific · 2024Article
- Systems modelling and simulation to guide targeted investments to reduce youth suicide and mental health problems in a low-middle-income country.BMC global and public health · 2024Article
- The PHEM-B toolbox of methods for incorporating the influences on Behaviour into Public Health Economic Models.BMC public health · 2024Article
- The current state of complex systems research on socioeconomic inequalities in health and health behavior-a systematic scoping review.The international journal of behavioral nutrition and physical activity · 2024Article
- Patterns of emergency department presentations for a youth mental health cohort: data-linkage cohort study.BJPsych open · 2023Article
- Article
- Unemployment and underemployment are causes of suicide.Science advances · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundReducing suicidal behaviour (SB) is a critical public health issue globally. The complex interplay of social determinants, service system factors, population demographics, and behavioural dynamics makes it extraordinarily difficult for decision makers to determine the nature and balance of investments required to have the greatest impacts on SB. Real-world experimentation to establish the optimal targeting, timing, scale, frequency, and intensity of investments required across the determinants is unfeasible. Therefore, this study harnesses systems modelling and simulation to guide population-level decision making that represent best strategic allocation of limited resources.
methodsUsing a participatory approach, and informed by a range of national, state, and local datasets, a system dynamics model was developed, tested, and validated for a regional population catchment. The model incorporated defined pathways from social determinants of mental health to psychological distress, mental health care, and SB. Intervention scenarios were investigated to forecast their impact on SB over a 20-year period.
resultsA combination of social connectedness programs, technology-enabled coordinated care, post-attempt assertive aftercare, reductions in childhood adversity, and increasing youth employment projected the greatest impacts on SB, particularly in a youth population, reducing self-harm hospitalisations (suicide attempts) by 28.5% (95% interval 26.3-30.8%) and suicide deaths by 29.3% (95% interval 27.1-31.5%). Introducing additional interventions beyond the best performing suite of interventions produced only marginal improvement in population level impacts, highlighting that 'more is not necessarily better.'
conclusionResults indicate that targeted investments in addressing the social determinants and in mental health services provides the best opportunity to reduce SB and suicide. Systems modelling and simulation offers a robust approach to leveraging best available research, data, and expert knowledge in a way that helps decision makers respond to the unique characteristics and drivers of SB in their catchments and more effectively focus limited health resources.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.