Evidence map›Paper›PMID 33706763›Full record

SynthesisWorld journal of emergency surgery : WJES2021

Evidence for use of damage control surgery and damage control interventions in civilian trauma patients: a systematic review.

Derek J Roberts, Niklas Bobrovitz, David A Zygun, Andrew W Kirkpatrick, Chad G Ball, Peter D Faris, Henry T Stelfox, Indications for Trauma Damage Control Surgery International Study Group

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in World journal of emergency surgery : WJES, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 4 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 4 syntheses or guidelines pooled it, 72 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Blood transfusion strategies for major bleeding in trauma.The Cochrane database of systematic reviews · 2025
    Pooled it
  4. Guideline
  5. Review
  6. Review
  7. Review
  8. Inflammatory Stewardship-A Perspective for Active Management of Acute Inflammation.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  9. Article
  10. Review
  11. Emergency Whipple procedure for traumatic pancreas-duodenum separation in a patient with multiorgan injury: a case report and review.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026
    Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Increased use of damage control laparotomy for emergency small bowel or colon surgery: does it affect patient outcomes?European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Derek J RobertsDivision of Vascular and Endovascular Surgery, University of Ottawa, Ottawa, ON, Canada. Derek.Roberts01@gmail.com.ORCID 0000-0001-6111-6291
Niklas BobrovitzNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
David A ZygunDivision of Critical Care Medicine, University of Alberta, Edmonton, AB, Canada.
Andrew W KirkpatrickDepartment of Surgery, University of Calgary, Calgary, AB, Canada.
Chad G BallDepartment of Surgery, University of Calgary, Calgary, AB, Canada.
Peter D FarisAlberta Health Sciences Research-Research Analytics, University of Calgary and the Foothills Medical Centre, Calgary, AB, Canada.
Henry T StelfoxDepartment of Critical Care Medicine, University of Calgary and Alberta Health Services, Calgary, AB, Canada.
Indications for Trauma Damage Control Surgery International Study Group
Alberta Health Services · CAUniversity of Alberta · CAOttawa Hospital · CAUniversity of Calgary · CAUniversity of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough damage control (DC) surgery is widely assumed to reduce mortality in critically injured patients, survivors often suffer substantial morbidity, suggesting that it should only be used when indicated. The purpose of this systematic review was to determine which indications for DC have evidence that they are reliable and/or valid (and therefore in which clinical situations evidence supports use of DC or that DC improves outcomes).

methodsWe searched 11 databases (1950-April 1, 2019) for studies that enrolled exclusively civilian trauma patients and reported data on the reliability (consistency of surgical decisions in a given clinical scenario) or content (surgeons would perform DC in that clinical scenario or the indication predicted use of DC in practice), construct (were associated with poor outcomes), or criterion (were associated with improved outcomes when DC was conducted instead of definitive surgery) validity for suggested indications for DC surgery or DC interventions.

resultsAmong 34,979 citations identified, we included 36 cohort studies and three cross-sectional surveys in the systematic review. Of the 59 unique indications for DC identified, 10 had evidence of content validity [e.g., a major abdominal vascular injury or a packed red blood cell (PRBC) volume exceeding the critical administration threshold], nine had evidence of construct validity (e.g., unstable patients with combined abdominal vascular and pancreas gunshot injuries or an iliac vessel injury and intraoperative acidosis), and six had evidence of criterion validity (e.g., penetrating trauma patients requiring > 10 U PRBCs with an abdominal vascular and multiple abdominal visceral injuries or intraoperative hypothermia, acidosis, or coagulopathy). No studies evaluated the reliability of indications.

conclusionsFew indications for DC surgery or DC interventions have evidence supporting that they are reliable and/or valid. DC should be used with respect for the uncertainty regarding its effectiveness, and only in circumstances where definitive surgery cannot be entertained.

Indexed as

Evidence-Based MedicineHumansSurvival AnalysisWounds and InjuriesDamage controlIndicationsMajor traumaSurgical procedures, operativeSystematic review

Identifiers

PMID33706763
PMCPMC7951941
OpenAlexW3110881046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.