ArticleBMC oral health2021
Microbiological findings in early and late implant loss: an observational clinical case-controlled study.
Article in BMC oral health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05900297 (Antibiotic Regimen for Patients Seeking Dental Implants Procedures), which is not on this map. Cited by 23 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Antibiotic Regimen for Patients Seeking Dental Implants Procedures
Who cites it
23 citing papers in PubMed.
- Aetiology of early implant failure: a scoping review.Clinical oral investigations · 2026Article
- Submucosal microbiota profile in peri-implant health, peri-implant mucositis, and different severity levels of peri-implantitis.BMC oral health · 2026Article
- The Prevalence of Early Implant Failure and Associated Risk Factors: A Retrospective Study.Journal of clinical and experimental dentistry · 2026Review
- Characterization of the oral microbiota in zygomatic versus dental implants: Implications for full-mouth rehabilitation.Journal of dental sciences · 2026Article
- hADMSC-YTZP seeding improves peri-implant bone repair through increased expression of BMP-2, ALP, and OPG.Scientific reports · 2025Article
- The Microbial Diversity and Biofilm Characteristics of d-PTFE Membranes Used for Socket Preservation: A Randomized Controlled Clinical Trial.Journal of functional biomaterials · 2025Article
- Microbiological findings of dental implants among irradiated head and neck cancer patients.Bioinformation · 2025Article
- Oral microbiota interactions with titanium implants: A pilot in-vivo and in-vitro study on the impact of peri-implantitis.PloS one · 2025Article
- Linking peri-implantitis to microbiome changes in affected implants, healthy implants, and saliva: a cross-sectional pilot study.Frontiers in cellular and infection microbiology · 2025Article
- The Influence of Selected Titanium Alloy Micro-Texture Parameters on Bacterial Adhesion.Materials (Basel, Switzerland) · 2024Article
- The Oral Microbiome of Peri-Implant Health and Disease: A Narrative Review.Dentistry journal · 2024Review
- Assessing peri-implant bacterial community structure: the effect of microbiome sample collection method.BMC oral health · 2024Article
- Peri-Implant Microbial Signature Shifts in Titanium, Zirconia and Ceria-Stabilized Zirconia Reinforced with Alumina Sites Subjected to Experimental Peri-Implantitis: A Preclinical Study in Dogs.Antibiotics (Basel, Switzerland) · 2024Article
- An In Vitro Study on the Application of Silver-Doped Platelet-Rich Plasma in the Prevention of Post-Implant-Associated Infections.International journal of molecular sciences · 2024Article
- Disparity in the Influence of Implant Provisional Materials on Human Gingival Fibroblasts with Different Phases of Cell Settlement: An In Vitro Study.International journal of molecular sciences · 2023Article
- The Microbiome of Peri-Implantitis: A Systematic Review of Next-Generation Sequencing Studies.Antibiotics (Basel, Switzerland) · 2023Review
- Scanning electron microscopic analysis of adherent bacterial biofilms associated with peri-implantitis.Clinical and experimental dental research · 2023Article
- Non-Surgical Therapy and Oral Microbiota Features in Peri-Implant Complications: A Brief Narrative Review.Healthcare (Basel, Switzerland) · 2023Review
- The Main Bacterial Communities Identified in the Sites Affected by Periimplantitis: A Systematic Review.Microorganisms · 2022Article
- Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundImplants are a predictable and well-established treatment method in dentistry. Nevertheless, looking at possible failures of dental implants, early and late loss have to be distinguished. The intent of the study was to report microbiological findings on the surface of implants with severe peri-implantitis, which had to be explanted.
methods53 specimens of implants from 48 patients without severe general illnesses have been examined. The groups investigated were implants that had to be removed in the period of osseointegration (early loss, 13 patients with 14 implants) or after the healing period (late loss, 14 patients with 17 implants). The implant losses were compared with two control groups (implants with no bone loss directly after completed osseointegration, two to four months after implant placement (17 patients with 17 implants) and implants with no bone loss and prosthetic restoration for more than three years (5 patients with 5 implants)). Data about the bacteria located in the peri-implant sulcus was collected using amplification and high throughput sequencing of the 16S rRNA gene.
resultsThe biofilm composition differed substantially between individuals. Both in early and late implant loss, Fusobacterium nucleatum and Porphyromonas gingivalis were found to be abundant. Late lost implants showed higher bacterial diversity and in addition higher abundances of Treponema, Fretibacterium, Pseudoramibacter and Desulfobulbus, while microbial communities of early loss implants were very heterogeneous and showed no significantly more abundant bacterial taxa.
conclusionsSpecific peri-implant pathogens were found around implants that were lost after a primarily uneventful osseointegration. P. gingivalis and F. nucleatum frequently colonized the implant in early and late losses and could therefore be characteristic for implant loss in general. In general, early lost implants showed also lower microbial diversity than late losses. However, the microbial results were not indicative of the causes of early and late losses.
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