Evidence map›Paper›PMID 33706736›Full record

ArticleBMC pulmonary medicine2021

Cockroach exposure and perceived stress interact to predict clinical outcomes in childhood asthma.

Felicia A Rabito, Derek Werthmann, Hua He, Aubrey S Madkour, Whitney D Arroyave, Michelle L Sever, Thomas A LaVeist

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pulmonary medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. The Impact of the Indoor Environment on Childhood Asthma.Current allergy and asthma reports · 2025
    Review
  2. Altered COVID-19 immunity in children with asthma by atopic status.The journal of allergy and clinical immunology. Global · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Felicia A RabitoDepartment of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, 1440 Canal Street, Suite 2016, New Orleans, LA, 70112, USA. rabito@tulane.edu.ORCID http://orcid.org/0000-0002-8820-6278
Derek WerthmannDepartment of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, 1440 Canal Street, Suite 2016, New Orleans, LA, 70112, USA.
Hua HeDepartment of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, 1440 Canal Street, Suite 2016, New Orleans, LA, 70112, USA.
Aubrey S MadkourDepartment of Global Community Health and Behavioral Sciences, School of Public Health and Tropical Medicine, Tulane University, 1440 Canal Street, Suite 2016, New Orleans, LA, 70112, USA.
Whitney D ArroyaveDepartment of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, 1440 Canal Street, Suite 2016, New Orleans, LA, 70112, USA.
Michelle L SeverPPD Government and Public Health Services , 3900 Paramount Parkway, Morrisville, NC, 27560, USA.
Thomas A LaVeistDepartment of Health Policy and Management, School of Public Health and Tropical Medicine, Tulane University, 1440 Canal Street, Suite 2016, New Orleans, LA, 70112, USA.
Tulane University · US

Funding

CDC HHS U01EH001130NCEH CDC HHS U01 EH001130U.S. Department of Housing and Urban Development LAHH0228-10
6 · The paper itself

Abstract

backgroundNonpharmacologic interventions for asthma management rely on identification and mitigation of important asthma triggers. Cockroach exposure is strongly associated with asthma morbidity. It is also associated with stress, another risk factor for asthma. Despite high prevalence of both in vulnerable populations, the impact of joint exposure has not been examined.

methodsParticipants included 173 children with asthma in New Orleans, Louisiana. Cockroach exposure was based on visual inspection using standard protocols. Caregiver stress was measured using Cohen's 4-item Perceived Stress Scale. Outcomes included unscheduled clinic or emergency department (ED) visits, hospitalization, and pulmonary function. Multivariable logistic regression was performed to assess independent effects of the exposure on the outcome and effect modification was examined in stratified analysis based on stress. Path analysis to explore the mediation effect by stress was performed using a probit link with parameters based on Bayes' method with non-informative priors.

resultsAdjusting for stress and other covariates, cockroach exposure was associated with unscheduled clinic/ED visits (aOR = 6.2; 95% CI 1.8, 21.7). Positive associations were also found for hospitalization and FEV

conclusionThe strong association between cockroach exposure and asthma morbidity is not due to uncontrolled confounding by stress. The combination of cockroach exposure and high stress, common in urban homes, are modifiable factors associated with poor asthma outcomes.

Indexed as

CockroachesEnvironmental ExposureAmbulatory CareAnimalsAsthmaBayes TheoremCaregiversChildEmergency Service, HospitalFemaleHospitalizationHumansLogistic ModelsLouisianaMaleMorbidityAsthma morbidityChildhood asthmaCockroach allergenPath analysisPerceived stress

Identifiers

PMID33706736
PMCPMC7953637
OpenAlexW3135907589

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.