Evidence map›Paper›PMID 33706729›Full record

Trial reportBMC musculoskeletal disorders2021

Transcranial direct current stimulation (a-tCDS) after subacromial injections in patients with subacromial pain syndrome: a randomized controlled pilot study.

Samuel Larrivée, Frédéric Balg, Guillaume Léonard, Sonia Bédard, Michel Tousignant, Patrick Boissy

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC musculoskeletal disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03967574 (Characterization and Temporal Evaluation of the Effects of Subacromial Corticosteroid Injections and Trans-cranial Direct Current Stimulation in Rotator Cuff Tendinopathy), which is not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03967574 nacompletednot on this map

Characterization and Temporal Evaluation of the Effects of Subacromial Corticosteroid Injections and Trans-cranial Direct Current Stimulation in Rotator Cuff Tendinopathy

TypeinterventionalSponsorUniversité de SherbrookeRan2015 to 2016Enrolled38ConditionsRotator Cuff Tendinosis, Rotator Cuff Impingement Syndrome, Rotator Cuff Impingement, Rotator Cuff InjuriesArmsTranscranial direct current stimulation
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Brain stimulation targets for chronic pain: Insights from meta-analysis, functional connectivity and literature review.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2024
    Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Samuel LarrivéeResearch Center on Aging CIUSSS Estrie CHUS, Sherbrooke, QC, Canada.
Frédéric BalgDepartment of Surgery, Division of Orthopedics, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada.
Guillaume LéonardResearch Center on Aging CIUSSS Estrie CHUS, Sherbrooke, QC, Canada.
Sonia BédardResearch Center CRCHUS, CIUSSS Estrie CHUS, Sherbrooke, QC, Canada.
Michel TousignantResearch Center on Aging CIUSSS Estrie CHUS, Sherbrooke, QC, Canada.
Patrick BoissyResearch Center on Aging CIUSSS Estrie CHUS, Sherbrooke, QC, Canada. patrick.boissy@usherbrooke.ca.ORCID http://orcid.org/0000-0001-6582-4519
Université de Sherbrooke · CACentre Hospitalier Universitaire de Sherbrooke · CA

Funding

Fond de Recherche en Enseignement en Orthopédie de Sherbrooke (FREOS) (CA) N/AUniversité de Sherbrooke Faculty of Medicine and Health Sciences N/A
6 · The paper itself

Abstract

backgroundSubacromial pain syndrome (SAPS) is a common complaint in orthopaedics. Subacromial corticosteroid injections (CSI) can relieve pain in the short term. Anodal transcranial direct current stimulation (a-tDCS) has been used for symptomatic pain relief in a variety of chronic pain conditions. The aim of this pilot study was to assess whether the application a-tDCS could enhance the symptomatic relief provided by CSI in patients affected by SAPS.

methodsThirty-eight participants (18 to 65-year-old) suffering from SAPS were recruited to have a CSI and randomly allocated to receive, 1 weeks post CSI, real a-tDCS (r-tDCS), sham tDCS (s-tDCS) or no intervention (Control). Upper limb function was measured 1 week prior to the CSI, at the 2- and 4-week follow-ups using self-administered questionnaires and physical measures. Self-reported pain and activity during each day were logged by the participants using visual analog scales (VAS). Differences between groups were tested using repeated-measures ANOVAs.

resultsPain VAS and the Single Assessment Numeric Evaluation scale (SANE) showed significant improvement from baseline 2 weeks and 4 weeks after CSI in all groups (p < 0.05). There were no significant group X time interaction 2 weeks following tDCS treatment in any of the variables.

conclusionAll groups showed significant improvement in pain VAS and SANE scores following the CSI. One session of a-tDCS treatment 2 weeks following CSI did not result in any additive or potentializing effects when compared to a s-tDCS or a control group.

trial registrationClinicalTrials.gov, NCT03967574 . Registered 30 May 2019 - Retrospectively registered.

Indexed as

Chronic PainTranscranial Direct Current StimulationAdolescentAdrenal Cortex HormonesAdultAgedHumansMiddle AgedPilot ProjectsUpper ExtremityYoung AdultAdrenal Cortex HormonesAccelerometryRotator cuff tendinitisShoulder activitySubacromial bursitisSubacromial pain syndrome

Identifiers

PMID33706729
PMCPMC7948354
OpenAlexW3134184245

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.