Evidence map›Paper›PMID 33706715›Full record

ArticleBMC medical research methodology2021

Outbreaks of publications about emerging infectious diseases: the case of SARS-CoV-2 and Zika virus.

Aziz Mert Ipekci, Diana Buitrago-Garcia, Kaspar Walter Meili, Fabienne Krauer, Nirmala Prajapati, Shabnam Thapa, Lea Wildisen, Lucia Araujo-Chaveron, Lukas Baumann, Sanam Shah and 7 more

Abstract read
In one paragraph

Article in BMC medical research methodology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Aziz Mert IpekciInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Diana Buitrago-GarciaInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Kaspar Walter MeiliDepartment of Epidemiology and Global Health, Umeå University, Umeå, Sweden.
Fabienne KrauerCentre for Ecological and Evolutionary Synthesis (CEES), University of Oslo, Oslo, Norway.
Nirmala PrajapatiÉcole des Hautes Études en Santé Publique (EHESP), Saint Denis, France.
Shabnam ThapaInstitute of Public Health, Jagiellonian University Medical College, Kraków, Poland.
Lea WildisenInstitute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.
Lucia Araujo-ChaveronÉcole des Hautes Études en Santé Publique (EHESP), Saint Denis, France.
Lukas BaumannDepartment of Internal Medicine, Kantonsspital Olten, Olten, Switzerland.
Sanam ShahÉcole des Hautes Études en Santé Publique (EHESP), Saint Denis, France.
Tessa WhiteleyÉcole des Hautes Études en Santé Publique (EHESP), Saint Denis, France.
Gonzalo Solís-GarcíaPediatrics Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Foteini TsotraSchool of Health and Related Research (ScHARR), University of Sheffield, Sheffield, UK.
Ivan ZhelyazkovSchool of Health and Related Research (ScHARR), University of Sheffield, Sheffield, UK.
Hira ImeriInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Nicola LowInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Michel Jacques CounotteInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland. michel.counotte@ispm.unibe.ch.ORCID 0000-0003-1039-6873

Funding

European Union's Horizon 2020 research and innovation programme - project EpiPose 101003688Swiss government excellence scholarship and the Swiss School of Public Health Global P3HS 2019.0774Swiss National Science Foundation 176233
6 · The paper itself

Abstract

backgroundOutbreaks of infectious diseases generate outbreaks of scientific evidence. In 2016 epidemics of Zika virus emerged, and in 2020, a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a pandemic of coronavirus disease 2019 (COVID-19). We compared patterns of scientific publications for the two infections to analyse the evolution of the evidence.

methodsWe annotated publications on Zika virus and SARS-CoV-2 that we collected using living evidence databases according to study design. We used descriptive statistics to categorise and compare study designs over time.

resultsWe found 2286 publications about Zika virus in 2016 and 21,990 about SARS-CoV-2 up to 24 May 2020, of which we analysed a random sample of 5294 (24%). For both infections, there were more epidemiological than laboratory science studies. Amongst epidemiological studies for both infections, case reports, case series and cross-sectional studies emerged first, cohort and case-control studies were published later. Trials were the last to emerge. The number of preprints was much higher for SARS-CoV-2 than for Zika virus.

conclusionsSimilarities in the overall pattern of publications might be generalizable, whereas differences are compatible with differences in the characteristics of a disease. Understanding how evidence accumulates during disease outbreaks helps us understand which types of public health questions we can answer and when.

Indexed as

Case-Control StudiesCOVID-19Cross-Sectional StudiesDisease OutbreaksHumansPandemicsPeriodicals as TopicPublicationsSARS-CoV-2Zika VirusZika Virus Infection

Identifiers

PMID33706715
PMCPMC7948668

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.