Evidence map›Paper›PMID 33706318›Full record

Observational studyRespiration; international review of thoracic diseases

Exploring the Relationship between Disease Awareness and Outcomes in Patients with Chronic Obstructive Pulmonary Disease.

Ilaria Baiardini, Marco Contoli, Angelo Guido Corsico, Carla Scognamillo, Fabio Ferri, Nicola Scichilone, Paola Rogliani, Fabiano Di Marco, Pierachille Santus, Fulvio Braido

Abstract readObservational Study
In one paragraph

Observational study in Respiration; international review of thoracic diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Health education using customized aids for patients with osteoporotic vertebral fractures- a non-randomized controlled study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Article
  9. Observational
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  11. Article
  12. Review
  13. Article
  14. The Importance of Self-Management in the Context of Personalized Care in COPD.International journal of chronic obstructive pulmonary disease · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ilaria BaiardiniRespiratory Unit for Continuity of Care, Department of Internal Medicine, University of Genova, Genoa, Italy, ilaria.baiardini@libero.it.
Marco ContoliRespiratory Diseases Department of Morphology, Surgery and Experimental Medicine-Università di Ferrara- Ferrara, Ferrara, Italy.
Angelo Guido CorsicoRespiratory Diseases Division, Medical Sciences and Infectious Diseases Department, IRCCS Policlinico San Matteo Foundation, and Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy.
Carla ScognamilloBoehringer Ingelheim, Milan, Italy.
Fabio FerriMediNeos Observational Research, Modena, Italy.
Nicola ScichiloneDipartimento Universitario PROMISE, Università di Palermo, UOC di Pneumologia, Policlinico Universitario P. Giaccone, Palermo, Italy.
Paola RoglianiRespiratory Medicine, Department of Experimental Medicine Università di Roma Tor Vergata,", Rome, Italy.
Fabiano Di MarcoDepartment of Health Sciences, Università degli Studi di Milano, Respiratory Unit, ASST Papa Giovanni XXIII, Bergamo, Italy.
Pierachille SantusDepartment of Biomedical and Clinical Sciences (DIBIC), Università degli Studi di Milano. Division of Respiratory Diseases, University Hospital "L. Sacco," ASST Fatebenefratelli-Sacco, Milan, Italy.
Fulvio BraidoRespiratory Unit for Continuity of Care, Department of Internal Medicine, University of Genova, Genoa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDisease awareness is a challenge in the management of chronic obstructive pulmonary disease (COPD).

objectivesThe aim of this analysis was to explore the association between COPD optimal and suboptimal awareness, clinical parameters, and the following patient-reported outcomes: modified Medical Research Council (mMRC), Treatment Satisfaction Questionnaire (TSQM-9), COPD Assessment Test (CAT), Morisky Medication-Taking Adherence Scale (MMAS-4), and Brief Illness Perception Questionnaire (B-IPQ).

methodsThis post hoc analysis of the SAT study included all enrolled patients for whom awareness (Disease Awareness in COPD Questionnaire - DACQ) was assessed at baseline and 12 months. DACQ scores ≥80 were considered an indicator of an optimal awareness.

results367 patients (25.8% women, median age 72 years) were included in the analysis. At enrollment, 74 patients (20.2%) had a DACQ score ≥80. Patients with suboptimal awareness, compared to those in which awareness was optimal, had higher median scores for CAT (p = 0.0001) and mMRC (p = 0.0031), a lower median TSQM-9 global score (p < 0.0001), and higher median B-IPQ score (p < 0.0001). The proportion of patients who had exacerbations during the previous year was higher in patients with suboptimal COPD awareness than in those with DACQ score ≥80 (42.8 vs. 21.4%, p = 0.0009). During the 12-month observation period, illness perception, adherence, and treatment satisfaction were found to be independent factors significantly associated with level of disease awareness.

conclusionThe results of our post hoc analysis suggest that patients' awareness of their COPD disease is related to both clinical outcomes and how they perceive and manage their condition.

Indexed as

Diagnostic Self EvaluationHealth BehaviorPulmonary Disease, Chronic ObstructiveSelf-ManagementTreatment Adherence and ComplianceAgedFemaleHealth Knowledge, Attitudes, PracticeHumansItalyMalePatient Reported Outcome MeasuresPatient SatisfactionSeverity of Illness IndexSurveys and QuestionnairesSymptom Flare UpAdherenceAwarenessChronic obstructive pulmonary diseasePatient-reported outcomes

Identifiers

PMID33706318
PMCPMC8220921

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.