Evidence map›Paper›PMID 33706158›Full record

ReviewBiosensors & bioelectronics2021

Electrochemical diagnostics of infectious viral diseases: Trends and challenges.

K Yugender Goud, K Koteshwara Reddy, Ahmed Khorshed, V Sunil Kumar, Rupesh K Mishra, Mohamed Oraby, Alyaa Hatem Ibrahim, Hern Kim, K Vengatajalabathy Gobi

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Biosensors & bioelectronics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 3 pooled it
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 3 syntheses or guidelines pooled it, 98 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 4 countries.

K Yugender GoudDepartment of NanoEngineering, University of California San Diego, La Jolla, CA, 92093, USA. Electronic address: ykotagiri@eng.ucsd.edu.
K Koteshwara ReddySmart Living Innovation Technology Centre, Department of Energy Science and Technology, Myongji University, Yongin, Gyeonggi-do, 17058, Republic of Korea. Electronic address: k.koteshwarreddy@gmail.com.
Ahmed KhorshedDepartment of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Sohag University, Sohag, 82524, Egypt. Electronic address: ahmed_khorshed@pharm.sohag.edu.eg.
V Sunil KumarDepartment of Chemistry, National Institute of Technology Warangal, Telangana, 506004, India.
Rupesh K MishraDepartment of NanoEngineering, University of California San Diego, La Jolla, CA, 92093, USA.
Mohamed OrabyDepartment of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Sohag University, Sohag, 82524, Egypt.
Alyaa Hatem IbrahimDepartment of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Sohag University, Sohag, 82524, Egypt.
Hern KimSmart Living Innovation Technology Centre, Department of Energy Science and Technology, Myongji University, Yongin, Gyeonggi-do, 17058, Republic of Korea. Electronic address: hernkim@mju.ac.kr.
K Vengatajalabathy GobiDepartment of Chemistry, National Institute of Technology Warangal, Telangana, 506004, India. Electronic address: drkvgobi@gmail.com.
Sohag University · EGMyongji University · KRNational Institute of Technology Warangal · INUniversity of California San Diego · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infectious diseases caused by viruses can elevate up to undesired pandemic conditions affecting the global population and normal life function. These in turn impact the established world economy, create jobless situations, physical, mental, emotional stress, and challenge the human survival. Therefore, timely detection, treatment, isolation and prevention of spreading the pandemic infectious diseases not beyond the originated town is critical to avoid global impairment of life (e.g., Corona virus disease - 2019, COVID-19). The objective of this review article is to emphasize the recent advancements in the electrochemical diagnostics of twelve life-threatening viruses namely - COVID-19, Middle east respiratory syndrome (MERS), Severe acute respiratory syndrome (SARS), Influenza, Hepatitis, Human immunodeficiency virus (HIV), Human papilloma virus (HPV), Zika virus, Herpes simplex virus, Chikungunya, Dengue, and Rotavirus. This review describes the design, principle, underlying rationale, receptor, and mechanistic aspects of sensor systems reported for such viruses. Electrochemical sensor systems which comprised either antibody or aptamers or direct/mediated electron transfer in the recognition matrix were explicitly segregated into separate sub-sections for critical comparison. This review emphasizes the current challenges involved in translating laboratory research to real-world device applications, future prospects and commercialization aspects of electrochemical diagnostic devices for virus detection. The background and overall progress provided in this review are expected to be insightful to the researchers in sensor field and facilitate the design and fabrication of electrochemical sensors for life-threatening viruses with broader applicability to any desired pathogens.

Indexed as

Antibodies, ViralBiosensing TechniquesElectrochemical TechniquesHumansMicrofluidic Analytical TechniquesSELEX Aptamer TechniqueVirus DiseasesAntibodies, ViralCOVID-19DiagnosticsElectrochemical biosensorsInfectious diseasesPoint of care (POC)Virus detection

Identifiers

PMID33706158
PMCPMC7921732
OpenAlexW3133898350

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.