ArticleEnvironment international2021
Dietary patterns and PFAS plasma concentrations in childhood: Project Viva, USA.
Article in Environment international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 63 citations in OpenAlex.
- Seafood and Neurocognitive Development in Children: A Systematic Review.Advances in nutrition (Bethesda, Md.) · 2025Pooled it
- Exposure to perfluoroalkyl and polyfluoroalkyl substances and pediatric obesity: a systematic review and meta-analysis.International journal of obesity (2005) · 2024Pooled it
- Pediatric effects of forever chemicals may last for a long time.Pediatric research · 2026Review
- Dietary and social predictors of PFAS exposure in Hispanic children from Northern Virginia.Journal of exposure science & environmental epidemiology · 2026Article
- A two-step Bayesian clustering approach to relate PFAS mixture profiles and dietary patterns in early pregnancy.Environmental research · 2026Article
- Occurrence and Dietary Exposure of Legacy and Emerging Per- and Polyfluoroalkyl Substances in Preprepared Meat and Aquatic Dishes - China, 2025.China CDC weekly · 2026Article
- Sociodemographic predictors of PFAS exposure among a combined sample of U.S. pregnant women: an Environmental influences on Child Health Outcomes (ECHO) public-use dataset analysis.Journal of exposure science & environmental epidemiology · 2026Article
- Associations of mid-childhood per- and polyfluoroalkyl substances and early childhood metals with mid-childhood antibody titers.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- Serum Levels of Per- and Polyfluoroalkyl Substances in Adults Aged 18 and Older in Relation to the Length of Residency in United States.Journal of immigrant and minority health · 2026Article
- Evaluating the geographic distribution of rural PFAS contamination and potential dietary sources of exposure.NPJ emerging contaminants · 2026Article
- Degree of food processing and serum poly- and perfluoroalkyl substance concentrations in the US National Health and Nutrition Examination Survey, 2003-2018.International journal of hygiene and environmental health · 2025Article
- Distribution of perfluorooctanoic acid in exposed female postpubertal pigs in thermal neutral or heat-stressed conditions.Toxicological sciences : an official journal of the Society of Toxicology · 2025Article
- Per- and poly-fluoroalkyl substances (PFAS) in circulation in a Canadian population: their association with serum-liver enzyme biomarkers and piloting a novel method to reduce serum-PFAS.Environmental health : a global access science source · 2025Article
- An oat fiber intervention for reducing PFAS body burden: A pilot study in male C57Bl/6 J mice.Toxicology and applied pharmacology · 2025Article
- Examining disparities in PFAS plasma concentrations: Impact of drinking water contamination, food access, proximity to industrial facilities and superfund sites.Environmental research · 2025Article
- Mid-Childhood Plasma Concentrations of Per- and Polyfluoroalkyl Substances, Modifiable Lifestyle Factors, and Bone Mineral Density Through Late Adolescence.Environmental science & technology · 2024Article
- Systematic evidence mapping of potential correlates of exposure for per- and poly-fluoroalkyl substances (PFAS) based on measured occurrence in biomatrices and surveys of dietary consumption and product use.International journal of hygiene and environmental health · 2024Review
- Evaluation of the Prime Diet Quality Score from Early Childhood Through Mid-Adolescence.The Journal of nutrition · 2024Article
- Characterizing Important Dietary Exposure Sources of Perfluoroalkyl Acids in Inuit Youth and Adults in Nunavik Using a Feature Selection Tool.Environmental health perspectives · 2024Article
- Impact of Environmental Exposures on Human Breast Milk Lipidome in Future Immune-Mediated Diseases.Environmental science & technology · 2024Article
Corrections and comments
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Authors and funding
9 authors at 6 institutions in 1 country.
Funding
Abstract
backgroundDiet is thought to account for most adult human exposure to per- and polyfluoroalkyl substances (PFAS). Children are particularly vulnerable to adverse health effects of PFAS and may have different eating habits than adults. However, studies of dietary patterns and PFAS in children are limited.
methodsWe studied 548 Boston-area children with food frequency questionnaire data (89 food items) in early childhood (median age 3.3 years) and plasma concentrations of 6 PFAS quantified in mid-childhood (median age 7.7 years). We used univariate linear regression to examine associations between each food item and PFAS, accounting for multiple comparisons. We next used reduced rank regression (RRR) to estimate overall percent variation in PFAS explained by diet and identify dietary patterns most correlated with PFAS. All models were adjusted for race/ethnicity, maternal education, and household income.
resultsIn univariate analyses, 2-(N-methyl-perfluorooctane sulfonamide) acetate (MeFOSAA) plasma concentrations were 17.8% (95% CI: 7.2, 29.5) and 17.0% (95% CI: 6.4, 28.7) higher per SD increment in intake of ice cream and soda, respectively. RRR identified 6 dietary patterns that together explained 18% variation in the plasma concentrations of the 6 PFAS, of which 50% was explained by a dietary pattern consisting of primarily packaged foods (including ice cream and soda) and fish. Children with higher intake of the packaged foods and fish dietary pattern had higher plasma concentrations of all PFAS, particularly MeFOSAA and PFOS.
conclusionsOur analysis examined food intake in association with several PFAS in children and identified dietary determinants that may be sources of PFAS exposure or reflect correlated lifestyle or toxicokinetic factors. Further investigation may help inform measures to modify childhood PFAS exposure.
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Registered trials
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