Evidence map›Paper›PMID 33706023›Full record

ArticleChild abuse & neglect2021

Adverse childhood events and cognitive function among young adults: Prospective results from the national longitudinal study of adolescent to adult health.

Misty A W Hawkins, Harley M Layman, Kyle T Ganson, Jennifer Tabler, Lucia Ciciolla, Cindy E Tsotsoros, Jason M Nagata

Open access · greenAbstract read
In one paragraph

Article in Child abuse & neglect, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
9.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it, 88 citations in OpenAlex.

  1. Pooled it
  2. The association between perinatal depressive symptoms and child neurodevelopment.American journal of obstetrics & gynecology MFM · 2024
    Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Effects of HIV and Adverse Childhood Experiences on Neurocognition.Journal of acquired immune deficiency syndromes (1999) · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Juvenile delinquency and cognitive function in adulthood: Differentiating violent and nonviolent behaviors and exploring multiple mechanisms.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2025
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Misty A W HawkinsOklahoma State University, Department of Psychology, Stillwater, OK, USA. Electronic address: misty.hawkins@okstate.edu.
Harley M LaymanOklahoma State University, Department of Psychology, Stillwater, OK, USA. Electronic address: hlayman@okstate.edu.
Kyle T GansonUniversity of Toronto, Factor-Inwentash Faculty of Social Work, Toronto, ON, Canada. Electronic address: kyle.ganson@utoronto.ca.
Jennifer TablerUniversity of Wyoming, Department of Criminal Justice and Sociology, Laramie, WY, USA. Electronic address: jtabler@uwyo.edu.
Lucia CiciollaOklahoma State University, Department of Psychology, Stillwater, OK, USA. Electronic address: lucia.ciciolla@okstate.edu.
Cindy E TsotsorosOklahoma State University, Department of Psychology, Stillwater, OK, USA. Electronic address: cindy.tsotsoros@okstate.edu.
Jason M NagataUniversity of California, Division of Adolescent and Young Adult Medicine, Department of Pediatrics, San Francisco, CA, USA. Electronic address: jason.nagata@ucsf.edu.
Oklahoma State University · USUniversity of California System · USUniversity of Toronto · CAUniversity of Wyoming · US

Funding

Wave IV Data CollectionP01HD031921 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HARRIS, KATHLEEN MULLAN · 1994 to 2020
$86.1M
The Impact of Maternal Adversity and Attachment Security on Infant Stress Reactivity: Prenatal Epigenetic PathwaysP20GM109097 · NIGMS · OSU CENTER FOR HEALTH SCIENCES · PI Dian Yu · 2016 to 2026
$22.8M
Cognitive and Self-Regulatory Mechanisms of Obesity Study (COSMOS)K23DK103941 · NIDDK · OKLAHOMA STATE UNIVERSITY STILLWATER · PI HAWKINS, MISTY · 2015 to 2019
$736k
Acute Inflammatory Effects of Weight Stigma in Overweight/ObesityF31HL152620 · NHLBI · OKLAHOMA STATE UNIVERSITY STILLWATER · PI KEIRNS, NATALIE · 2020 to 2021
$62k
NHLBI NIH HHS F31 HL152620NICHD NIH HHS P01 HD031921NIDDK NIH HHS K23 DK103941NIGMS NIH HHS P20 GM109097
6 · The paper itself

Abstract

backgroundAdverse childhood experiences (ACEs) may have lasting impacts on cognition.

objectiveTo determine if ACE exposure is prospectively associated with cognition in young adults. We hypothesized that deprivation- and threat-type ACEs as well as higher cumulative ACE exposure predict poorer cognition. PARTICIPANTS &

settingParticipants were from the National Longitudinal Study of Adolescent to Adult Health (Add Health), a prospective cohort investigation of U.S. adolescents followed to adulthood. Current study participants were 18-24 years old (Wave III), 24-32 years old (Wave IV), and 31-42 years old (Wave V). The maximum Wave IV sample was 12,288 adults; Wave V was 1277 adults.

methodsHistory of ACEs were assessed at Wave III. Three cognitive indicators were assessed at Wave IV and Wave V using the Rey Auditory Verbal Learning Test (immediate and delayed verbal memory) and the Digit-Span Backward Task (working memory).

resultsThe deprivation ACE of not-having-basic-needs met was associated with poorer working (β = 0.14, CI

conclusionsHigher ACEs, especially deprivation-type, were prospectively linked to poorer cognition. Early wide-scale screening/tailored treatments addressing ACEs and cognitive function may be warranted.

Indexed as

Adverse Childhood ExperiencesAdolescentAdultCognitionCohort StudiesHumansLongitudinal StudiesProspective StudiesYoung AdultAdverse childhood experiencesCognitive functionEarly life adversityExecutive functionMemory

Identifiers

PMID33706023
PMCPMC11610377
OpenAlexW3135760826

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.