Evidence map›Paper›PMID 33705983›Full record

ArticleJournal of the American College of Surgeons2021

Validation of the Artificial Intelligence-Based Predictive Optimal Trees in Emergency Surgery Risk (POTTER) Calculator in Emergency General Surgery and Emergency Laparotomy Patients.

Majed W El Hechi, Lydia R Maurer, Jordan Levine, Daisy Zhuo, Mohamad El Moheb, George C Velmahos, Jack Dunn, Dimitris Bertsimas, Haytham Ma Kaafarani

Abstract readValidation Study
PubMed Publisher
In one paragraph

Article in Journal of the American College of Surgeons, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 63 citations in OpenAlex.

  1. Pooled it
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  4. Artificial intelligence for predicting 30-day mortality after emergency laparotomy.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
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  19. Cardiac risk stratification and adverse outcomes in surgically managed patients with isolated traumatic spine injuries.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Majed W El HechiDivision of Trauma, Emergency Surgery, and Surgical Critical Care, Massachusetts General Hospital, Boston, MA.
Lydia R MaurerDivision of Trauma, Emergency Surgery, and Surgical Critical Care, Massachusetts General Hospital, Boston, MA.
Jordan LevineInterpretable AI, Boston, MA.
Daisy ZhuoInterpretable AI, Boston, MA.
Mohamad El MohebDivision of Trauma, Emergency Surgery, and Surgical Critical Care, Massachusetts General Hospital, Boston, MA.
George C VelmahosDivision of Trauma, Emergency Surgery, and Surgical Critical Care, Massachusetts General Hospital, Boston, MA.
Jack DunnInterpretable AI, Boston, MA.
Dimitris BertsimasInterpretable AI, Boston, MA; Massachusetts Institute of Technology, Cambridge, MA.
Haytham Ma KaafaraniDivision of Trauma, Emergency Surgery, and Surgical Critical Care, Massachusetts General Hospital, Boston, MA. Electronic address: hkaafarani@mgh.harvard.edu.
Massachusetts General Hospital · USMassachusetts Institute of Technology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Predictive Optimal Trees in Emergency Surgery Risk (POTTER) tool is an artificial intelligence-based calculator for the prediction of 30-day outcomes in patients undergoing emergency operations. In this study, we sought to assess the performance of POTTER in the emergency general surgery (EGS) population in particular.

methodsAll patients who underwent EGS in the 2017 American College of Surgeons NSQIP database were included. The performance of POTTER in predicting 30-day postoperative mortality, morbidity, and 18 specific complications was assessed using the c-statistic metric. As a subgroup analysis, the performance of POTTER in predicting the outcomes of patients undergoing emergency laparotomy was assessed.

resultsA total of 59,955 patients were included. Median age was 50 years and 51.3% were women. POTTER predicted mortality (c-statistic = 0.93) and morbidity (c-statistic = 0.83) extremely well. Among individual complications, POTTER had the highest performance in predicting septic shock (c-statistic = 0.93), respiratory failure requiring mechanical ventilation for 48 hours or longer (c-statistic = 0.92), and acute renal failure (c-statistic = 0.92). Among patients undergoing emergency laparotomy, the c-statistic performances of POTTER in predicting mortality and morbidity were 0.86 and 0.77, respectively.

conclusionsPOTTER is an interpretable, accurate, and user-friendly predictor of 30-day outcomes in patients undergoing EGS. POTTER could prove useful for bedside counseling of patients and their families and for benchmarking of EGS care.

Indexed as

Artificial IntelligenceAdultAgedBenchmarkingDatabases, FactualDecision TreesEmergency Service, HospitalEmergency TreatmentFeasibility StudiesFemaleHospital MortalityHumansLaparotomyMaleMiddle AgedPostoperative Complications

Identifiers

PMID33705983
OpenAlexW3133637958

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.