ArticleNeurogastroenterology and motility2021
Evaluating esophageal motility beyond primary peristalsis: Assessing esophagogastric junction opening mechanics and secondary peristalsis in patients with normal manometry.
Article in Neurogastroenterology and motility, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06883175 (Evolution of the Chicago Classification), which is not on this map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evolution of the Chicago Classification: Bridging Physiology and Mechanics
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it.
- SAGES-EAES systematic review and meta-analysis for the use of FLIP/impedance planimetry in the surgical work-up and management of GERD, achalasia, and gastroparesis.Surgical endoscopy · 2026Pooled it
- Biomechanical Assessment During High-Resolution Impedance Manometry Enhances Characterization of Inconclusive Esophagogastric Junction Outflow Obstruction.Neurogastroenterology and motility · 2026Article
- Machine Learning Clustering Identifies Achalasia-Spectrum Phenotypes in Distal Esophageal Spasm.Journal of neurogastroenterology and motility · 2026Article
- A novel approach to studying human orogastric transit with an ingestible bionic device. An early feasibility study.Physiological measurement · 2026Article
- Validation of Functional Lumen Imaging Probe Panometry Esophageal Motility Classification Version 2.0: A Study of 805 Patients.Neurogastroenterology and motility · 2025Article
- Modeling based insights into mechanical dysfunction in esophageal motility disorders.PLoS computational biology · 2025Article
- Assessing Treatment Outcomes in Achalasia Using 4-Dimensional High-resolution Impedance Manometry.Journal of neurogastroenterology and motility · 2025Article
- When Manometry and Functional Lumen Imaging Probe Disagree: The Current Limitations of the Chicago Classification Version 4.0 and Probable Extended Indications of Functional Lumen Imaging Probe.Journal of neurogastroenterology and motility · 2025Review
- Endoscopic Prediction of Achalasia: Putting the CART Before the CARS.Neurogastroenterology and motility · 2025Article
- Endoscopic Sedation Type During FLIP Panometry Does Not Significantly Impact FLIP Motility Classification Relative to Manometry.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2025Article
- Diagnostic Accuracy of Timed Barium Esophagram for Achalasia.Gastroenterology · 2025Article
- Functional Lumen Imaging Probe Panometry.Gastrointestinal endoscopy clinics of North America · 2025Review
- A Standardized Approach to Performing and Interpreting Functional Lumen Imaging Probe Panometry for Esophageal Motility Disorders: The Dallas Consensus.Gastroenterology · 2025Article
- The Esophageal Response to Distension on Functional Lumen Imaging Probe Panometry Is Minimally Changed by Conscious Sedation in Healthy Asymptomatic Subjects.Journal of neurogastroenterology and motility · 2025Article
- Defining lower esophageal sphincter physiomechanical states among esophageal motility disorders using functional lumen imaging probe panometry.Neurogastroenterology and motility · 2024Article
- Enhancing Chicago Classification diagnoses with functional lumen imaging probe-mechanics (FLIP-MECH).Neurogastroenterology and motility · 2024Article
- Effects of Cholecystokinin on Esophageal Motor Response to Distension in Asymptomatic Volunteers.Journal of neurogastroenterology and motility · 2024Article
- Impact of Body Composition on Esophagogastric Junction Opening Measures: Discordant FLIP and Manometric Findings Are More Common With Increased Body Mass Index.The American journal of gastroenterology · 2024Article
- Secondary peristalsis and esophagogastric junction distensibility in symptomatic post-fundoplication patients.Neurogastroenterology and motility · 2024Article
- Impedance planimetry and panometry (EndoFLIP™) can replace manometry in preoperative anti-reflux surgery assessment.Surgical endoscopy · 2024Article
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Authors and funding
6 authors.
Funding
Abstract
backgroundFunctional luminal imaging probe (FLIP) Panometry assesses the esophageal response to distention and may complement the assessment of primary peristalsis on high-resolution manometry (HRM). We aimed to investigate whether FLIP Panometry provides complementary information in patients with normal esophageal motility on HRM.
methodsAdult patients that completed FLIP and had an HRM classification of normal motility were retrospectively identified for inclusion. 16-cm FLIP studies performed during endoscopy were evaluated to assess EGJ distensibility, secondary peristalsis, and identify an abnormal response to distention involving sustained LES contraction (sLESC). Clinical characteristics and esophagram were assessed when available. KEY
resultsOf 164 patients included (mean(SD) age 48(16) years, 75% female), 111 (68%) had normal Panometry with EGJ-distensibility index (DI) ≥2.0 mm CONCLUSIONS & INFERENCES: Symptomatic patients with normal esophageal motility on HRM predominantly have normal FLIP Panometry; however, abnormal FLIP findings can be observed. While abnormal Panometry findings appear clinically relevant via an association with abnormal bolus retention, complementary tests, such as provocative maneuvers with HRM and timed barium esophagram, are useful to determine clinical context.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.