Evidence map›Paper›PMID 33705497›Full record

ReviewPLoS pathogens2021

Clostridioides difficile biofilms: A mechanism of persistence in the gut?

Lucy R Frost, Jeffrey K J Cheng, Meera Unnikrishnan

Abstract readReview
In one paragraph

Review in PLoS pathogens, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Biological Mechanisms of Polyphenols againstInfectious disorders drug targets · 2025
    Pooled it
  2. The prevalence and molecular epidemiology ofEmerging microbes & infections · 2026
    Observational
  3. Disruption ofJournal of medical microbiology · 2026
    Article
  4. Review
  5. Acidification-dependent suppression ofInfection and immunity · 2026
    Article
  6. Article
  7. Review
  8. Acidification-dependent suppression ofbioRxiv : the preprint server for biology · 2026
    Article
  9. Microbiology spectrum · 2026
    Article
  10. Review
  11. Review
  12. Gut microbes · 2025
    Article
  13. Article
  14. Review
  15. Article
  16. Effect of Pefloxacin onAntibiotics (Basel, Switzerland) · 2025
    Article
  17. Article
  18. Journal of bacteriology · 2025
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lucy R FrostDivision of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry, United Kingdom.ORCID 0000-0003-0750-778X
Jeffrey K J ChengDivision of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry, United Kingdom.ORCID 0000-0002-4093-7872
Meera UnnikrishnanDivision of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry, United Kingdom.ORCID 0000-0001-5417-9331

Funding

Biotechnology and Biological Sciences Research Council 1782606Biotechnology and Biological Sciences Research Council 1897785
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BiofilmsClostridioidesClostridioides difficileClostridium InfectionsGastrointestinal TractHumans

Identifiers

PMID33705497
PMCPMC7951904

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.