Evidence map›Paper›PMID 33705419›Full record

ArticlePloS one2021

Serological markers and risk factors associated with Hepatitis B virus infection among Federal Capital Territory prison inmates, Nigeria: Should we be concerned?

Chioma Cindy Dan-Nwafor, Ikeola Adeoye, Kehinde Aderemi, Martins Onuoha, Elizabeth Adedire, Adebobola Bashorun, Damaris Osunkwo, Saheed Gidado, Muhammad Balogun, Suleiman Idris and 3 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
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  3. Review
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  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Chioma Cindy Dan-NwaforNigeria Field Epidemiology and Laboratory Training Programme, Decatur, Georgia, United States of America.ORCID 0000-0002-3294-2276
Ikeola AdeoyeDepartment of Epidemiology and Medical Statistics, University of Ibadan, Ibadan, Nigeria.
Kehinde AderemiDepartment of Medical Microbiology and Parasitology, College of Medicine University of Ibadan, Ibadan, Nigeria.
Martins OnuohaNigeria Field Epidemiology and Laboratory Training Programme, Decatur, Georgia, United States of America.
Elizabeth AdedireNigeria Field Epidemiology and Laboratory Training Programme, Decatur, Georgia, United States of America.
Adebobola BashorunNigeria Field Epidemiology and Laboratory Training Programme, Decatur, Georgia, United States of America.
Damaris OsunkwoNigeria Field Epidemiology and Laboratory Training Programme, Decatur, Georgia, United States of America.
Saheed GidadoNigeria Field Epidemiology and Laboratory Training Programme, Decatur, Georgia, United States of America.
Muhammad BalogunNigeria Field Epidemiology and Laboratory Training Programme, Decatur, Georgia, United States of America.
Suleiman IdrisDepartment of Community Medicine, Ahmadu Bello University, Zaria, Nigeria.
Ibrahim Ade-YusufNigerian Prisons Service Headquarters, Abuja, Nigeria.
Ekpedeme UdomNigerian Prisons Service Headquarters, Abuja, Nigeria.
Patrick NgukuNigeria Field Epidemiology and Laboratory Training Programme, Decatur, Georgia, United States of America.
University of Ibadan · NGAhmadu Bello University · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHepatitis B virus (HBV) infection is hyper-endemic in Nigeria. Prisons are high-risk environments for the spread of infectious diseases. Worldwide, seroprevalence of HBV infection is substantially higher among individuals in correctional facilities when compared to general population. We determined the seroprevalence and risk factors associated with HBV infection among Kuje prison inmates, Nigeria. MATERIAL AND

methodsWe conducted a prison facility based cross-sectional study. Interviewer administered questionnaires were used to obtain information on participants socio-demographic characteristics, HBV risk factors, previous HBV test and vaccination history. Blood samples collected from participants were analysed for HBsAg, HBsAb, HBcAb, HBeAg and HBeAb markers using rapid lateral chromatographic immunoassay kit. Univariate, bivariate, and multivariate analysis were performed.

resultsA total of 271 inmates (63 convicts and 208 awaiting trial inmates) were recruited into the study as participants. The mean age of the participants was 32.7 SD±9 years. HBV seroprevalence (HBsAg) of 13.7% (95% CI: 9.8-18.3) was found. 55.4% (95% CI: 49.2-61.4) of inmates were susceptible to HBV infection, 20.7% (95%CI; 16.0-26.0) had past HBV infection while 10.3% (95% CI: 7.0-14.6) had acquired natural or artificial HBV immunity. Factors found to be associated with current HBV infection (HBsAg) include age-group ≤25years (aOR = 8.0,95% CI: 2.9-22.3), being ever married (aOR = 4.2, 95% CI: 1.7-10.4) and history of alcohol consumption (aOR = 3.4, 95% CI: 1.3-8.4).

conclusionThis study reveals a high seroprevalence of HBV infection among Kuje Prison inmates, hence the need to introduce prison-focused health intervention initiatives such as HBV screening, vaccination and care to reduce the transmission of HBV infection among inmates and ultimately the general population.

Indexed as

AdultCross-Sectional StudiesHepatitis BHepatitis B Surface AntigensHumansMaleMarital StatusMiddle AgedNigeriaPrisonersRisk FactorsSeroepidemiologic StudiesYoung AdultHepatitis B Surface Antigens

Identifiers

PMID33705419
PMCPMC7951833
OpenAlexW3134175428

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.