Evidence map›Paper›PMID 33705239›Full record

ReviewExpert review of clinical pharmacology2021

Epidemiology, pathogenesis, clinical presentations, diagnosis and treatment of COVID-19: a review of current evidence.

Sayeeda Rahman, Maria Teresa Villagomez Montero, Kherie Rowe, Rita Kirton, Frank Kunik

Open access · greenAbstract readReview
In one paragraph

Review in Expert review of clinical pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 132 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
132citing papers in PubMed, 2 pooled it
17.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

132 citing papers in PubMed, 2 syntheses or guidelines pooled it, 291 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Efficacy of low-intensity pulsed ultrasound in the treatment of COVID-19 pneumonia.Ultraschall in der Medizin (Stuttgart, Germany : 1980) · 2023
    Trial
  5. Review
  6. Article
  7. Review
  8. Article
  9. Remdesivir in COVID-19: pros and cons.Frontiers in pharmacology · 2026
    Review
  10. Article
  11. Article
  12. Article
  13. Low Dose Cyclophospahamide is a Feasable Mobilization Regimen in the Covid-19 Era: A Single Center Study from Türkiye.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

72 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sayeeda RahmanSchool of Medicine, American University of Integrative Sciences (AUIS), Bridgetown, Barbados.ORCID https://orcid.org/0000-0002-7005-8801
Maria Teresa Villagomez MonteroSchool of Medicine, American University of Integrative Sciences (AUIS), Bridgetown, Barbados.
Kherie RoweSchool of Medicine, American University of Integrative Sciences (AUIS), Bridgetown, Barbados.
Rita KirtonSchool of Medicine, American University of Integrative Sciences (AUIS), Bridgetown, Barbados.
Frank KunikSchool of Medicine, American University of Integrative Sciences (AUIS), Bridgetown, Barbados.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe COVID-19 pandemic has created a public health crisis, infected millions of people, and caused a significant number of deaths. SARS-CoV-2 transmits from person to person through several routes, mainly via respiratory droplets, which makes it difficult to contain its spread into the community. Here, we provide an overview of the epidemiology, pathogenesis, clinical presentation, diagnosis, and treatment of COVID-19. AREAS COVERED: Direct person-to-person respiratory transmission has rapidly amplified the spread of coronavirus. In the absence of any clinically proven treatment options, the current clinical management of COVID-19 includes symptom management, infection prevention and control measures, optimized supportive care, and intensive care support in severe or critical illness. Developing an effective vaccine is now a leading research priority. Some vaccines have already been approved by the regulatory authorities for the prevention of COVID-19. EXPERT OPINION: General prevention and protection measures regarding the containment and management of the second or third waves are necessary to minimize the risk of infection. Until now, four vaccines reported variable efficacies of between 62-95%, and two of them (Pfizer/BioNTech and Moderna) received FDA emergency use authorization. Equitable access and effective distribution of these vaccines in all countries will save millions of lives.

Indexed as

Antiviral AgentsCOVID-19COVID-19 VaccinesHumansInfectious Disease Incubation PeriodPublic Health AdministrationSARS-CoV-2Antiviral AgentsCOVID-19 Vaccinesclinical presentationsCOVID-19diagnosisepidemiologypathogenesissars-cov-2treatment

Identifiers

PMID33705239
PMCPMC8095162
OpenAlexW3135057655

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.