Evidence map›Paper›PMID 33704731›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2021

Imaging and Isolation of Extravasation-Participating Endothelial and Melanoma Cells During Angiopellosis.

Tyler A Allen, Ke Cheng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Tyler A AllenDivision of Medical Oncology, Department of Medicine, Duke University Medical Center, Durham, NC, USA.
Ke ChengDepartment of Molecular Biomedical Sciences and Comparative Medicine Institute, North Carolina State University, Raleigh, NC, USA. kcheng3@ncsu.edu.

Funding

Enhancing vascular delivery of stem cells and microparticlesR01HL137093 · NHLBI · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI CHENG, KE · 2017 to 2020
$1.5M
NHLBI NIH HHS R01 HL137093
6 · The paper itself

Abstract

Cancer mortality rates are primarily a result of cancer metastasis. Recent advances in microscopy technology allow for the imaging of circulating tumor cells (CTCs) as they extravasate (exit) blood vessels, a key step in the metastasis process. Here, we describe the use of intravital microscopy techniques to image and isolate both extravasating melanoma CTCs and the extravasation-participating endothelial cells. These techniques can be used as a means to study cancer metastasis and as a screening tool for anticancer therapeutics.

Indexed as

Endothelial CellsIntravital MicroscopyMelanoma, ExperimentalNeoplastic Cells, CirculatingZebrafishAnimalsAnimals, Genetically ModifiedCell Line, TumorNeoplasm MetastasisAngiopellosisCancer Exodus HypothesisCirculating tumor cellsExtravasationIntravital microscopyLight sheet microscopyMetastasisTumor cell isolationTumor infusionZebrafish

Identifiers

PMID33704731
PMCPMC8299427

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.