Evidence map›Paper›PMID 33704717›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2021

Multi-Marker Immunomagnetic Enrichment of Circulating Melanoma Cells.

Aaron B Beasley, Emmanuel Acheampong, Weitao Lin, Elin S Gray

Open access · greenAbstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Aaron B BeasleySchool of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.
Emmanuel AcheampongSchool of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.
Weitao LinSchool of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.
Elin S GraySchool of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia. e.gray@ecu.edu.au.
Edith Cowan University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Within the last decade, circulating tumor cells (CTCs) have emerged as a promising biomarker for prognostication, treatment monitoring, and detection of markers of treatment resistance, and their isolation can be used as a minimally invasive means of profiling tumors across multiple body sites. However, CTCs represent a minuscule fraction of the total circulating cells in a patient. Therefore, sensitive isolation methods are needed for the detection and downstream analysis of these cells. Herein we describe a sensitive method for melanoma CTC isolation using a multi-marker immunomagnetic bead method. This method has been purposely optimized to detect CTCs in melanoma patients.

Indexed as

Antigens, NeoplasmAntineoplastic Agents, ImmunologicalBiomarkers, TumorCell Culture TechniquesCell Line, TumorHumansImmunomagnetic SeparationLeukocytes, MononuclearMelanomaNeoplastic Cells, CirculatingAntigens, NeoplasmAntineoplastic Agents, ImmunologicalBiomarkers, TumorCirculating tumor cells (CTCs )Immunomagnetic beadsMulti-marker

Identifiers

PMID33704717
OpenAlexW3134821147

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.