Evidence map›Paper›PMID 33704597›Full record

ReviewCurrent cardiology reports2021

Clinical Implications of the ISCHEMIA Trial: Invasive vs Conservative Approach in Stable Coronary Disease.

Jamal Choudhary, Sarah Chiu, Priyanka Bhugra, Behnood Bikdeli, Azhar Supariwala, Rajiv Jauhar, Saurav Chatterjee

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current cardiology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Jamal ChoudharyFrank H. Netter, MD School of Medicine, Quinnipiac University, North Haven, CT, USA.
Sarah ChiuDepartment of Internal Medicine, Kaiser Permanente Los Angeles Medical Center, Los Angeles, CA, USA.
Priyanka BhugraDepartment of Internal Medicine, Houston Methodist Hospital, Houston, TX, USA.
Behnood BikdeliCardiovascular Medicine Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Azhar SupariwalaSouth Shore University Hospital, Northwell Health, Zucker School of Medicine, New York, NY, USA.
Rajiv JauharSandra Atlas Bass Heart Hospital, Manhasset, NY, 11030, USA.
Saurav ChatterjeeDivision of Cardiovascular Medicine, Long Island Jewish Medical Center, Northwell Health, Zucker School of Medicine, 270-05 76th Street, New Hyde Park, New York, NY, USA. sauravchatterjeemd@gmail.com.ORCID http://orcid.org/0000-0002-1241-5030
Northwell Health · USBrigham and Women's Hospital · USHofstra University · USKaiser Permanente · USMethodist Hospital · USQuinnipiac University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewTo identify key strengths and weaknesses of the International Study of Comparative Health Effectiveness with Medical and Invasive Approaches (ISCHEMIA) trial and explore its clinical implications in patients with stable ischemic heart disease. RECENT

findingsPrevious studies have shown inconsistent benefit of early angiography and revascularization in patients with stable ischemic heart disease. The ISCHEMIA trial showed no significant reduction in mortality or cardiovascular outcomes in patients undergoing early angiography and revascularization with guideline-directed medical therapy compared to patients on medical therapy alone in specific patient population with stable coronary artery disease. The ISCHEMIA trial provides insights into invasive versus pharmacological treatment for patients with stable ischemic heart disease. Though it may have reduced applicability given its broad exclusion criteria, it offers useful information about the utility of non-invasive imaging modalities for selecting optimal revascularization candidates.

Indexed as

Coronary Artery DiseaseMyocardial IschemiaCoronary AngiographyCoronary Artery BypassHumansIschemiaMyocardial RevascularizationCardiac catheterizationGuideline-directed medical therapyIschemic heart diseaseRevascularization

Identifiers

PMID33704597
OpenAlexW3135361633

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.