Evidence map›Paper›PMID 33704067›Full record

ArticleeLife2021

The dimeric Golgi protein Gorab binds to Sas6 as a monomer to mediate centriole duplication.

Agnieszka Fatalska, Emma Stepinac, Magdalena Richter, Levente Kovacs, Zbigniew Pietras, Martin Puchinger, Gang Dong, Michal Dadlez, David M Glover

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 4 countries.

Agnieszka Fatalska *Department of Genetics, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0002-1720-4742
Emma Stepinac *Department of Medical Biochemistry, Max Perutz Labs, Medical University of Vienna, Vienna, Austria.
Magdalena Richter *Department of Genetics, University of Cambridge, Cambridge, United Kingdom.
Levente KovacsDepartment of Genetics, University of Cambridge, Cambridge, United Kingdom.
Zbigniew PietrasInstitute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland.
Martin PuchingerDepartment of Structural and Computational Biology, Max Perutz Labs, University of Vienna, Vienna, Austria.
Gang DongDepartment of Medical Biochemistry, Max Perutz Labs, Medical University of Vienna, Vienna, Austria.ORCID 0000-0001-9745-8103
Michal DadlezInstitute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland.
David M GloverDepartment of Genetics, University of Cambridge, Cambridge, United Kingdom.
California Institute of Technology · USInstitute of Biochemistry and Biophysics, Polish Academy of Sciences · PLMax Perutz Labs · ATAstraZeneca (United Kingdom) · GBUniversity of Vienna · AT

Funding

Generation of Diverse Centrosomes, Cilia and Flagellae During DevelopmentR01NS113930 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI GLOVER, DAVID M · 2020 to 2024
$2.5M
Austrian Science Fund FWF P 28231NINDS NIH HHS R01 NS113930Wellcome Trust 202855/Z/16/Z
6 · The paper itself

Abstract

The duplication and ninefold symmetry of the

Indexed as

AnimalsCentriolesDrosophila melanogasterDrosophila ProteinsGolgi Matrix ProteinsLarvaMutationDrosophila ProteinsGolgi Matrix ProteinsSas-6 protein, Drosophilacell biologycentriole duplicationD. melanogasterGolgiGorabmolecular biophysicsRab6Sas6structural biology

Identifiers

PMID33704067
PMCPMC8009671
OpenAlexW3135817942

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.