ArticleCirculation research2021
MIR503HG Loss Promotes Endothelial-to-Mesenchymal Transition in Vascular Disease.
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Article in Circulation research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.
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50citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 4% of its field
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Who cites it
50 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.
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- Protocol for quantitative image analysis of alizarin red staining to assess osteogenesis in cultured cells.STAR protocols · 2026Article
- Cross-Platform Analysis of Endothelial Transcriptomic Changes Associated with Diabetes.Research square · 2026Article
- Dynamic cellular programs of human cardiac allograft rejection revealed by spatial transcriptomics.Nature cardiovascular research · 2026Article
- Vein graft failure: Pathophysiology, detection, prevention and emerging therapeutic strategies.Pharmacological reviews · 2026Review
- Improved RNA-DNA interaction calling suggests RNA-based gene regulation of phenotypic transitions.Nucleic acids research · 2026Article
- DOT1L Drives Endothelial-to-Mesenchymal Transition and Fibrotic Vascular Remodeling via H3K79 Methylation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Transcriptional landscape of pulmonary artery endothelium reveals subpopulation- and disease-specific remodeling signatures.Communications biology · 2026Article
- Endothelial to mesenchymal transition in cardiovascular diseases: molecular insights and clinical perspectives.European heart journal · 2026Review
- Endothelial PTBP1 Deletion in Transplanted Cardiac Tissue Limits Cardiac Allograft Vasculopathy.bioRxiv : the preprint server for biology · 2026Article
- Endothelial-to-mesenchymal transition in the central nervous system: A potential therapeutic target to combat age-related vascular fragility.The Journal of pharmacology and experimental therapeutics · 2025Review
- TheNon-coding RNA · 2025Article
- The senescence-like activity of BMS-470539 is associated with anti-fibrotic actions in models of dermal fibrosis.Arthritis research & therapy · 2025Article
- Long non-coding RNA HMGCR suppresses vascular remodeling in streptozotocin-induced type 1 diabetic rats via interaction with THOC5.European journal of medical research · 2025Article
- Loss of conserved long non-coding RNA MIR503HG leads to altered NOTCH pathway signalling and left ventricular non-compaction cardiomyopathy.Cardiovascular research · 2025Article
- Mechanistic insights and emerging therapeutic strategies targeting endothelial dysfunction in cardiovascular diseases.Archives of pharmacal research · 2025Review
- Exosomes Derived from Dialysis Patients' Serum Enhance Endothelial-Mesenchymal Transition and Calcification in Endothelial Cells.Kidney360 · 2025Article
- Broadening horizons: molecular mechanisms and disease implications of endothelial-to-mesenchymal transition.Cell communication and signaling : CCS · 2025Review
- Targeting endothelial cells: the pathological mechanisms and therapeutic innovations in pulmonary arterial hypertension.Frontiers in cell and developmental biology · 2025Review
- Precision Medicine for Pulmonary Vascular Disease: The Future Is Now (2023 Grover Conference Series).Pulmonary circulation · 2025Article
Corrections and comments
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Authors and funding
30 authors at 10 institutions in 6 countries.
João P MonteiroThe Queen's Medical Research Institute, Centre for Cardiovascular Science (J.P.M., J.R., A. Caudrillier, J.P.S., A.-M.S., T.D., A.S., L. Deng, S.-H.C., K.S., A.T., T.M., J.I., P.W.F.H., L. Denby, A. Caporali, A.H.B.), University of Edinburgh, Edinburgh, Scotland.
Julie Rodor *The Queen's Medical Research Institute, Centre for Cardiovascular Science (J.P.M., J.R., A. Caudrillier, J.P.S., A.-M.S., T.D., A.S., L. Deng, S.-H.C., K.S., A.T., T.M., J.I., P.W.F.H., L. Denby, A. Caporali, A.H.B.), University of Edinburgh, Edinburgh, Scotland.
Axelle CaudrillierThe Queen's Medical Research Institute, Centre for Cardiovascular Science (J.P.M., J.R., A. Caudrillier, J.P.S., A.-M.S., T.D., A.S., L. Deng, S.-H.C., K.S., A.T., T.M., J.I., P.W.F.H., L. Denby, A. Caporali, A.H.B.), University of Edinburgh, Edinburgh, Scotland.
Jessica P ScanlonThe Queen's Medical Research Institute, Centre for Cardiovascular Science (J.P.M., J.R., A. Caudrillier, J.P.S., A.-M.S., T.D., A.S., L. Deng, S.-H.C., K.S., A.T., T.M., J.I., P.W.F.H., L. Denby, A. Caporali, A.H.B.), University of Edinburgh, Edinburgh, Scotland.
Ana-Mishel SpiroskiThe Queen's Medical Research Institute, Centre for Cardiovascular Science (J.P.M., J.R., A. Caudrillier, J.P.S., A.-M.S., T.D., A.S., L. Deng, S.-H.C., K.S., A.T., T.M., J.I., P.W.F.H., L. Denby, A. Caporali, A.H.B.), University of Edinburgh, Edinburgh, Scotland.
Tatiana DudnakovaThe Queen's Medical Research Institute, Centre for Cardiovascular Science (J.P.M., J.R., A. Caudrillier, J.P.S., A.-M.S., T.D., A.S., L. Deng, S.-H.C., K.S., A.T., T.M., J.I., P.W.F.H., L. Denby, A. Caporali, A.H.B.), University of Edinburgh, Edinburgh, Scotland.
Beatrice Pflüger-MüllerInstitute for Cardiovascular Physiology, Goethe University, Frankfurt, Germany (B.P.-M., M.S.L., R.P.B.).
Alena ShmakovaThe Queen's Medical Research Institute, Centre for Cardiovascular Science (J.P.M., J.R., A. Caudrillier, J.P.S., A.-M.S., T.D., A.S., L. Deng, S.-H.C., K.S., A.T., T.M., J.I., P.W.F.H., L. Denby, A. Caporali, A.H.B.), University of Edinburgh, Edinburgh, Scotland.
Alex von KriegsheimEdinburgh Cancer Research UK Centre, Institute of Genetics and Molecular Medicine (A.v.K.), University of Edinburgh, Edinburgh, Scotland.
Lin Deng
Richard S TaylorThe Roslin Institute and Royal (Dick) School of Veterinary Studies (R.S.T.), University of Edinburgh, Edinburgh, Scotland.
John R Wilson-KanamoriThe Queen's Medical Research Institute, Centre for Inflammation Research (J.R.W.-K., N.C.H.), University of Edinburgh, Edinburgh, Scotland.
Shiau-Haln Chen
Kevin Stewart
Adrian Thomson
Tijana MitićThe Queen's Medical Research Institute, Centre for Cardiovascular Science (J.P.M., J.R., A. Caudrillier, J.P.S., A.-M.S., T.D., A.S., L. Deng, S.-H.C., K.S., A.T., T.M., J.I., P.W.F.H., L. Denby, A. Caporali, A.H.B.), University of Edinburgh, Edinburgh, Scotland.
John D McClureInstitute of Cardiovascular and Medical Sciences, British Heart Foundation (BHF) Glasgow Centre, University of Glasgow, Glasgow, United Kingdom (J.D.M., A.C.B.).
Jean IynikkelThe Queen's Medical Research Institute, Centre for Cardiovascular Science (J.P.M., J.R., A. Caudrillier, J.P.S., A.-M.S., T.D., A.S., L. Deng, S.-H.C., K.S., A.T., T.M., J.I., P.W.F.H., L. Denby, A. Caporali, A.H.B.), University of Edinburgh, Edinburgh, Scotland.
Patrick W F HadokeThe Queen's Medical Research Institute, Centre for Cardiovascular Science (J.P.M., J.R., A. Caudrillier, J.P.S., A.-M.S., T.D., A.S., L. Deng, S.-H.C., K.S., A.T., T.M., J.I., P.W.F.H., L. Denby, A. Caporali, A.H.B.), University of Edinburgh, Edinburgh, Scotland.
Laura DenbyThe Queen's Medical Research Institute, Centre for Cardiovascular Science (J.P.M., J.R., A. Caudrillier, J.P.S., A.-M.S., T.D., A.S., L. Deng, S.-H.C., K.S., A.T., T.M., J.I., P.W.F.H., L. Denby, A. Caporali, A.H.B.), University of Edinburgh, Edinburgh, Scotland.
Angela C BradshawInstitute of Cardiovascular and Medical Sciences, British Heart Foundation (BHF) Glasgow Centre, University of Glasgow, Glasgow, United Kingdom (J.D.M., A.C.B.).
Paola CarusoBHF Cambridge (CRE), University of Cambridge, Cambridge, United Kingdom (P.C., N.W.M.).
Nicholas W MorrellBHF Cambridge (CRE), University of Cambridge, Cambridge, United Kingdom (P.C., N.W.M.).
Jason C KovacicThe Zena and Michael A. Wiener Cardiovascular Institute, School of Medicine at Mount Sinai, New York, New York (J.C.K.).
Igor UlitskyDepartment of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel (I.U.).
Neil C HendersonThe Queen's Medical Research Institute, Centre for Inflammation Research (J.R.W.-K., N.C.H.), University of Edinburgh, Edinburgh, Scotland.
Andrea CaporaliThe Queen's Medical Research Institute, Centre for Cardiovascular Science (J.P.M., J.R., A. Caudrillier, J.P.S., A.-M.S., T.D., A.S., L. Deng, S.-H.C., K.S., A.T., T.M., J.I., P.W.F.H., L. Denby, A. Caporali, A.H.B.), University of Edinburgh, Edinburgh, Scotland.
Matthias S LeisegangInstitute for Cardiovascular Physiology, Goethe University, Frankfurt, Germany (B.P.-M., M.S.L., R.P.B.).
Ralf P BrandesInstitute for Cardiovascular Physiology, Goethe University, Frankfurt, Germany (B.P.-M., M.S.L., R.P.B.).
Andrew H BakerThe Queen's Medical Research Institute, Centre for Cardiovascular Science (J.P.M., J.R., A. Caudrillier, J.P.S., A.-M.S., T.D., A.S., L. Deng, S.-H.C., K.S., A.T., T.M., J.I., P.W.F.H., L. Denby, A. Caporali, A.H.B.), University of Edinburgh, Edinburgh, Scotland.
MRC Centre for Reproductive Health · GBGoethe University Frankfurt · DEBritish Heart Foundation · GBCentre for Inflammation Research · GBUniversity of Cambridge · GBAbbott (Sweden) · SEEdinburgh Cancer Research · GBRoslin Institute · GBVictor Chang Cardiac Research Institute · AUWeizmann Institute of Science · IL
Funding
Therapeutic Mechanisms of Cardiac Progenitors in Ischemic CardiomyopathyR01HL135093 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI FISH, KENNETH MICHAEL, KOVACIC, JASON CIRIL · 2017 to 2020
$3.4MUnderstanding the Molecular Mechanisms of Fibromuscular DysplasiaR01HL148167 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KADIAN-DODOV, DANIELLA, KOVACIC, JASON CIRIL · 2020 to 2023
$2.8MToward Therapeutic Manipulation of Endothelial to Mesenchymal TransitionR01HL130423 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ISHIKAWA, KIYOTAKE, KOVACIC, JASON CIRIL · 2016 to 2020
$2.1MBritish Heart Foundation CH/09/001/25945British Heart Foundation CH/11/2/28733British Heart Foundation FS/16/38/32351British Heart Foundation FS/18/40/33650British Heart Foundation PG/20/10347British Heart Foundation PG/21/10624British Heart Foundation RG/14/3/30706British Heart Foundation SP/17/3/33020European Research Council 338991NHLBI NIH HHS R01 HL130423NHLBI NIH HHS R01 HL135093NHLBI NIH HHS R01 HL148167Wellcome Trust 208402
Abstract
[Figure: see text].
Indexed as
Epithelial-Mesenchymal TransitionAnimalsHeterogeneous-Nuclear RibonucleoproteinsHumansHuman Umbilical Vein Endothelial CellsHypertension, PulmonaryMicePolypyrimidine Tract-Binding ProteinRNA, Long NoncodingTranscriptomeVascular RemodelingHeterogeneous-Nuclear Ribonucleoproteinslong non-coding RNA MIR503HG, humanPolypyrimidine Tract-Binding ProteinPTBP1 protein, humanRNA, Long Noncodingendothelial cellslncRNAmicroRNAspulmonary arterial hypertensionvascular remodeling
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