Evidence map›Paper›PMID 33694119›Full record

ArticleEnvironmental science and pollution research international2021

Acute toxicity and biomarker responses in Gammarus locusta amphipods exposed to copper, cadmium, and the organochlorine insecticide dieldrin.

Mohamed Dellali, Amel Douggui, Abdel Halim Harrath, Lamjed Mansour, Saleh Alwasel, Hamouda Beyrem, Thomas Gyedu-Ababio, Melissa Rohal-Lupher, Fehmi Boufahja

Abstract read
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In one paragraph

Article in Environmental science and pollution research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Proteomic and in silico characterization of stress-responsive proteins in the prawn penaeus indsicus under sublethal copper toxicity.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 4 countries.

Mohamed DellaliFaculty of Sciences of Bizerte, Laboratory of Environment Biomonitoring, Coastal Ecology and Ecotoxicology Unit, University of Carthage, 7021, Zarzouna, Tunisia.
Amel DougguiFaculty of Sciences of Bizerte, Laboratory of Environment Biomonitoring, Coastal Ecology and Ecotoxicology Unit, University of Carthage, 7021, Zarzouna, Tunisia.
Abdel Halim HarrathZoology Department, College of Science, King Saud University, Box 2455, Riyadh, 11451, Saudi Arabia.
Lamjed MansourZoology Department, College of Science, King Saud University, Box 2455, Riyadh, 11451, Saudi Arabia.
Saleh AlwaselZoology Department, College of Science, King Saud University, Box 2455, Riyadh, 11451, Saudi Arabia.
Hamouda BeyremFaculty of Sciences of Bizerte, Laboratory of Environment Biomonitoring, Coastal Ecology and Ecotoxicology Unit, University of Carthage, 7021, Zarzouna, Tunisia.
Thomas Gyedu-AbabioUniversity of South Africa, Pretoria, South Africa.
Melissa Rohal-LupherTexas Water Development Board, 1700 North Congress Avenue, Austin, TX, 78701, USA.
Fehmi BoufahjaFaculty of Sciences of Bizerte, Laboratory of Environment Biomonitoring, Coastal Ecology and Ecotoxicology Unit, University of Carthage, 7021, Zarzouna, Tunisia. fehmiboufahja@yahoo.fr.
University of Carthage · TNKing Saud University · SATexas Water Development Board · USUniversity of South Africa · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The toxicity of copper, cadmium, and dieldrin in adult Gammarus locusta (a marine amphipod) is currently unclear. Thus, G. locusta from the North Lake of Tunis were subjected to acute toxicity tests to assess LC50s at 48-96 h and to biomarker response tests through the assessment of catalase and acetylcholinesterase activities and malondialdehyde levels. The present study demonstrated the abilities of a chlorinated hydrocarbon pesticide (dieldrin) induce to oxidative stress and neurotoxicity. The comparison of metal toxicity showed that G. locusta was more sensitive to cadmium than copper. The three stressors caused significant inductions of all three biomarkers in a concentration-dependent manner. Catalase induction was dependent on exposure duration for all pollutants, while only copper led to increased malondialdehyde with longer exposure times. Catalase induction and malondialdehyde increase appeared to be sex dependent for all three pollutants. The neurotoxic effects of the pollutants were concentration dependent according to inhibition of acetylcholinesterase activity. In conclusion, catalase, malondialdehyde, and acetylcholinesterase are efficient biomarkers of copper, cadmium, and dieldrin in G. locusta.

Indexed as

AmphipodaInsecticidesWater Pollutants, ChemicalAnimalsBiomarkersCadmiumCopperDieldrinBiomarkersCadmiumCopperDieldrinInsecticidesWater Pollutants, ChemicalAcute toxicityBiomarkersCadmiumCopperDieldrinGammarus locusta

Identifiers

PMID33694119
OpenAlexW3135616671

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.