Evidence map›Paper›PMID 33694014›Full record

ArticleTropical animal health and production2021

Single nucleotide polymorphisms of leptin gene in five Ethiopian indigenous cattle breeds and the Korean Hanwoo breed.

Ayele Mandefro, Tesfaye Sisay, Kwan-Suk Kim, Zewdu Edea, Rocktotpal Konwarh, Hailu Dadi

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In one paragraph

Article in Tropical animal health and production, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Ayele MandefroDepartment of Biotechnology, Addis Ababa Science and Technology University, P.O. Box 16417, Addis Ababa, Ethiopia.ORCID http://orcid.org/0000-0003-0778-6723
Tesfaye SisayInstitute of Biotechnology, Addis Ababa University, P.O. Box 1176, Addis Ababa, Ethiopia.
Kwan-Suk KimDepartment of Animal Sciences, Chungbuk National University, Cheongju, Chungbuk, 361-763, South Korea.
Zewdu EdeaDepartment of Animal Sciences, Chungbuk National University, Cheongju, Chungbuk, 361-763, South Korea.
Rocktotpal KonwarhDepartment of Biotechnology, Addis Ababa Science and Technology University, P.O. Box 16417, Addis Ababa, Ethiopia.ORCID https://orcid.org/0000-0003-4767-4531
Hailu DadiEthiopian Biotechnology Institute, P.O. Box 2490, Addis Ababa, Ethiopia. edenhailu@yahoo.com.
Addis Ababa Science and Technology University · ETChungbuk National University · KRAddis Ababa University · ETEthiopian Public Health Institute · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Considering the escalating number of scientific reports on the association between the leptin gene and diverse physiological traits and performance of cattle populations, this study was directed towards identifying SNPs in the leptin gene among five indigenous cattle breeds of Ethiopia. DNA samples were extracted from the nasal swabs of the Ethiopian indigenous cattle breeds: Arsi (n = 18), Horro (n = 20), Begait (n = 21), Boran (n = 19), and Fogera (n = 17) and the Korean Hanwoo (a representative taurine breed) (n = 20), followed by PCR amplification of exon 2 and exon 3 regions of the leptin gene and sequence analysis of the PCR products. Five SNPs, two (generating missense mutations) on exon 2 and three (generating silent mutations) on exon 3 regions, were explicated in this study. Allele frequency and genotype frequency distribution pertaining to the SNPs were recorded for the studied cattle breeds besides the minor allele frequency and deviation from the Hardy-Weinberg equilibrium. Positive F

Indexed as

Polymorphism, Single NucleotideAnimalsCattleEthiopiaGene FrequencyGenotypeLeptinPhylogenyRepublic of KoreaLeptinCattle populationEthiopiaGenetic diversityHaplotypeLeptin geneSNP

Identifiers

PMID33694014
OpenAlexW3134508862

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.