Evidence map›Paper›PMID 33693996›Full record

ArticleEuropean radiology2021

Deep learning-based reconstruction may improve non-contrast cerebral CT imaging compared to other current reconstruction algorithms.

Luuk J Oostveen, Frederick J A Meijer, Frank de Lange, Ewoud J Smit, Sjoert A Pegge, Stefan C A Steens, Martin J van Amerongen, Mathias Prokop, Ioannis Sechopoulos

Abstract read
In one paragraph

Article in European radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Luuk J OostveenDepartment of Medical Imaging, Radboud University Medical Center, P.O. Box 9101 (route 766), 6500 HB, Nijmegen, The Netherlands. Luuk.Oostveen@radboudumc.nl.ORCID http://orcid.org/0000-0003-0445-9436
Frederick J A MeijerDepartment of Medical Imaging, Radboud University Medical Center, P.O. Box 9101 (route 766), 6500 HB, Nijmegen, The Netherlands.
Frank de LangeDepartment of Medical Imaging, Radboud University Medical Center, P.O. Box 9101 (route 766), 6500 HB, Nijmegen, The Netherlands.
Ewoud J SmitDepartment of Medical Imaging, Radboud University Medical Center, P.O. Box 9101 (route 766), 6500 HB, Nijmegen, The Netherlands.
Sjoert A PeggeDepartment of Medical Imaging, Radboud University Medical Center, P.O. Box 9101 (route 766), 6500 HB, Nijmegen, The Netherlands.
Stefan C A SteensDepartment of Medical Imaging, Radboud University Medical Center, P.O. Box 9101 (route 766), 6500 HB, Nijmegen, The Netherlands.
Martin J van AmerongenDepartment of Medical Imaging, Radboud University Medical Center, P.O. Box 9101 (route 766), 6500 HB, Nijmegen, The Netherlands.
Mathias ProkopDepartment of Medical Imaging, Radboud University Medical Center, P.O. Box 9101 (route 766), 6500 HB, Nijmegen, The Netherlands.
Ioannis SechopoulosDepartment of Medical Imaging, Radboud University Medical Center, P.O. Box 9101 (route 766), 6500 HB, Nijmegen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate image quality and reconstruction times of a commercial deep learning reconstruction algorithm (DLR) compared to hybrid-iterative reconstruction (Hybrid-IR) and model-based iterative reconstruction (MBIR) algorithms for cerebral non-contrast CT (NCCT).

methodsCerebral NCCT acquisitions of 50 consecutive patients were reconstructed using DLR, Hybrid-IR and MBIR with a clinical CT system. Image quality, in terms of six subjective characteristics (noise, sharpness, grey-white matter differentiation, artefacts, natural appearance and overall image quality), was scored by five observers. As objective metrics of image quality, the noise magnitude and signal-difference-to-noise ratio (SDNR) of the grey and white matter were calculated. Mean values for the image quality characteristics scored by the observers were estimated using a general linear model to account for multiple readers. The estimated means for the reconstruction methods were pairwise compared. Calculated measures were compared using paired t tests.

resultsFor all image quality characteristics, DLR images were scored significantly higher than MBIR images. Compared to Hybrid-IR, perceived noise and grey-white matter differentiation were better with DLR, while no difference was detected for other image quality characteristics. Noise magnitude was lower for DLR compared to Hybrid-IR and MBIR (5.6, 6.4 and 6.2, respectively) and SDNR higher (2.4, 1.9 and 2.0, respectively). Reconstruction times were 27 s, 44 s and 176 s for Hybrid-IR, DLR and MBIR respectively.

conclusionsWith a slight increase in reconstruction time, DLR results in lower noise and improved tissue differentiation compared to Hybrid-IR. Image quality of MBIR is significantly lower compared to DLR with much longer reconstruction times. KEY POINTS: • Deep learning reconstruction of cerebral non-contrast CT results in lower noise and improved tissue differentiation compared to hybrid-iterative reconstruction. • Deep learning reconstruction of cerebral non-contrast CT results in better image quality in all aspects evaluated compared to model-based iterative reconstruction. • Deep learning reconstruction only needs a slight increase in reconstruction time compared to hybrid-iterative reconstruction, while model-based iterative reconstruction requires considerably longer processing time.

Indexed as

Deep LearningAlgorithmsHumansRadiation DosageRadiographic Image Interpretation, Computer-AssistedTomography, X-Ray ComputedBrainDeep learningTomography, X-ray computed

Identifiers

PMID33693996
PMCPMC8270865

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.