ReviewGenetics2021
Chemosensory signal transduction in Caenorhabditis elegans.
Review in Genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 94 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
94 citing papers in PubMed, 147 citations in OpenAlex.
- Article
- Synchronization properties in C. elegans: Relating behavioral circuits to structural and functional neuronal connectivity.PLoS computational biology · 2026Article
- A lipid-sensitive food choice behavior influences aging outcomes from a longevity-promoting diet.The FEBS journal · 2026Article
- Neural sequences underlying directed turning in Caenorhabditis elegans.Nature neuroscience · 2026Article
- Article
- Stereotypical interciliary contacts in abioRxiv : the preprint server for biology · 2026Article
- A stereotyped glial attachment determines the morphology and function of neuronal cilia.bioRxiv : the preprint server for biology · 2026Article
- Induction and regulation of reversible suspended animation in C. elegans.Nature communications · 2026Article
- A lateralized sensory signaling pathway mediates context-dependent olfactory plasticity inProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Induction and regulation of a reversible form of suspended animation inbioRxiv : the preprint server for biology · 2026Article
- Efficient pheromone navigation via antagonistic detectors in Caenorhabditis elegans male.Nature communications · 2026Article
- TheJournal of nematology · 2026Review
- Memsensing by surface ion migration within Debye length.Nature materials · 2026Article
- Effects of Vitamin C Supplementation on Tetrabenazine Treatment in a Caenorhabditis elegans Huntington's Disease Model.microPublication biology · 2026Article
- ThebioRxiv : the preprint server for biology · 2025Article
- Volatile and non-volatile pathogen cues shape host extracellular vesicles production in pre-infection response.Nature communications · 2025Article
- Article
- Satiety, TAX-4, and OSM-9 tune the attraction of Caenorhabditis elegans nematodes to microbial fermentation products.G3 (Bethesda, Md.) · 2025Article
- Wild strains reveal natural variation in C. elegans avoidance behaviors.G3 (Bethesda, Md.) · 2025Article
- Investigating the Structural Basis of Diacetyl Recognition by the G-Protein-Coupled Receptor ODR-10 inThe journal of physical chemistry. B · 2025Article
34 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
Chemosensory neurons translate perception of external chemical cues, including odorants, tastants, and pheromones, into information that drives attraction or avoidance motor programs. In the laboratory, robust behavioral assays, coupled with powerful genetic, molecular and optical tools, have made Caenorhabditis elegans an ideal experimental system in which to dissect the contributions of individual genes and neurons to ethologically relevant chemosensory behaviors. Here, we review current knowledge of the neurons, signal transduction molecules and regulatory mechanisms that underlie the response of C. elegans to chemicals, including pheromones. The majority of identified molecules and pathways share remarkable homology with sensory mechanisms in other organisms. With the development of new tools and technologies, we anticipate that continued study of chemosensory signal transduction and processing in C. elegans will yield additional new insights into the mechanisms by which this animal is able to detect and discriminate among thousands of chemical cues with a limited sensory neuron repertoire.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.