ArticleAmerican journal of hypertension2021
Medication Adherence: Expanding the Conceptual Framework.
Article in American journal of hypertension, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Oral anticoagulant switching in patients with atrial fibrillation: a long-term cohort study using population-level administrative data.International journal of clinical pharmacy · 2026Article
- Patient perspectives on drug recalls in the Netherlands: a qualitative study.International journal of clinical pharmacy · 2026Article
- Development of the treatment adherence scale for rheumatic diseases.Clinical rheumatology · 2026Article
- Artificial intelligence approaches to predicting treatment non-adherence in chronic diseases: a narrative review.Frontiers in digital health · 2026Review
- Assessment of Adherence to Medication and Its Association with Health-Related Quality of Life Among Hypertensive Patients in the United Arab Emirates.Patient preference and adherence · 2026Article
- The Role of Religiosity on Racial/Ethnic Disparities in Non-adherence to Antihypertensive Medications.Journal of racial and ethnic health disparities · 2025Article
- Non-Adherence to Treatment Among Patients Attending a Public Primary Healthcare Setting in South Africa: Prevalence and Associated Factors.International journal of environmental research and public health · 2025Article
- Medication Adherence in the Real World: Lessons from the Diuretic Comparison Project.Journal of clinical medicine · 2025Article
- Translation and Validation of the Medication Understanding and Use Self-Efficacy Scale Among Patients With Type 2 Diabetes in Taiwan.Health expectations : an international journal of public participation in health care and health policy · 2025Article
- Enhancing primary care for older adults: the safety, efficacy, and adherence (SEA) team-based care model to reduce adverse medication outcomes.Frontiers in public health · 2025Article
- Differences in COVID-19 Vaccination and Experiences among Patients with Hypertension in Colombia and Jamaica during the COVID-19 Pandemic.International journal of environmental research and public health · 2024Article
- Current Gaps in the Provision of Safe and Effective Anticoagulation in Atrial Fibrillation and the Potential for Factor XI-Directed Therapeutics.Critical pathways in cardiology · 2024Review
- Article
- Factor Analysis of the Brazilian Questionnaire on Adherence to Ketogenic Dietary Therapy: Keto-Check.Nutrients · 2023Article
- Pre-stroke Adherence to Hypertension Medications in a Bi-racial United States Stroke Belt.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2023Article
- Factors Associated with Medication Adherence among Community-Dwelling Older People with Frailty and Pre-Frailty in China.International journal of environmental research and public health · 2022Article
- Time Preference for Immediate Gratification: Associations With Low Medication Adherence and Uncontrolled Blood Pressure.American journal of hypertension · 2022Article
- Review
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Authors and funding
8 authors.
Funding
Abstract
Interventions targeting traditional barriers to antihypertensive medication adherence have been developed and evaluated, with evidence of modest improvements in adherence. Translation of these interventions into population-level improvements in adherence and clinical outcomes among older adults remains suboptimal. From the Cohort Study of Medication Adherence among Older adults (CoSMO), we evaluated traditional barriers to antihypertensive medication adherence among older adults with established hypertension (N = 1,544; mean age = 76.2 years, 59.5% women, 27.9% Black, 24.1% and 38.9% low adherence by proportion of days covered (i.e., PDC <0.80) and the 4-item Krousel-Wood Medication Adherence Scale (i.e., K-Wood-MAS-4 ≥1), respectively), finding that they explained 6.4% and 14.8% of variance in pharmacy refill and self-reported adherence, respectively. Persistent low adherence rates, coupled with low explanatory power of traditional barriers, suggest that other factors warrant attention. Prior research has investigated explicit attitudes toward medications as a driver of adherence; the roles of implicit attitudes and time preferences (e.g., immediate vs. delayed gratification) as mechanisms underlying adherence behavior are emerging. Similarly, while associations of individual-level social determinants of health (SDOH) and medication adherence are well reported, there is growing evidence about structural SDOH and specific pathways of effect. Building on published conceptual models and recent evidence, we propose an expanded conceptual framework that incorporates implicit attitudes, time preferences, and structural SDOH, as emerging determinants that may explain additional variation in objectively and subjectively measured adherence. This model provides guidance for design, implementation, and assessment of interventions targeting sustained improvement in implementation medication adherence and clinical outcomes among older women and men with hypertension.
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