Evidence map›Paper›PMID 33693441›Full record

ReviewGlobal medical genetics2020

Genetics of Dentofacial and Orthodontic Abnormalities.

Praveen Kumar Neela, Anjana Atteeri, Pavan Kumar Mamillapalli, Vasu Murthy Sesham, Sreekanth Keesara, Jaya Chandra, Udayini Monica, Vasavi Mohan

Abstract readReview
In one paragraph

Review in Global medical genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Association between tooth agenesis and root morphology assessed by periapical radiographs : Retrospective cross-sectional observational study.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2026
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  9. Observational
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  13. Analysis ofGlobal medical genetics · 2021
    Article
  14. Medicina (Kaunas, Lithuania) · 2021
    Article
  15. Missense polymorphisms potentially involved in mandibular prognathism.Journal of oral biology and craniofacial research
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Praveen Kumar NeelaDepartment of Orthodontics, Kamineni Institute of Dental Sciences, Narketpally, India.
Anjana AtteeriDepartment of Orthodontics, Kamineni Institute of Dental Sciences, Narketpally, India.
Pavan Kumar MamillapalliDepartment of Orthodontics, Kamineni Institute of Dental Sciences, Narketpally, India.
Vasu Murthy SeshamDepartment of Orthodontics, Kamineni Institute of Dental Sciences, Narketpally, India.
Sreekanth KeesaraDepartment of Orthodontics, Kamineni Institute of Dental Sciences, Narketpally, India.
Jaya ChandraDepartment of Orthodontics, Kamineni Institute of Dental Sciences, Narketpally, India.
Udayini MonicaDepartment of Orthodontics, Kamineni Institute of Dental Sciences, Narketpally, India.
Vasavi MohanDepartment of Genetics and Molecular Medicine, Vasavi Medical and Research Centre, Hyderabad, Telangana, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of craniofacial complex and dental structures is a complex and delicate process guided by specific genetic mechanisms. Genetic and environmental factors can influence the execution of these mechanisms and result in abnormalities. An insight into the mechanisms and genes involved in the development of orofacial and dental structures has gradually gained by pedigree analysis of families and twin studies as well as experimental studies on vertebrate models. The development of novel treatment techniques depends on in-depth knowledge of the various molecular or cellular processes and genes involved in the development of the orofacial complex. This review article focuses on the role of genes in the development of nonsyndromic orofacial, dentofacial variations, malocclusions, excluding cleft lip palate, and the advancements in the field of molecular genetics and its application to obtain better treatment outcomes.

Indexed as

dentofacial variationsgenesgeneticsmalocclusionpolymorphism

Identifiers

PMID33693441
PMCPMC7938796

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.