Evidence map›Paper›PMID 33693060›Full record

ArticleTrauma surgery & acute care open2021

Determination of optimal deployment strategy for REBOA in patients with non-compressible hemorrhage below the diaphragm.

Nicholas L Johnson, Charles E Wade, Erin E Fox, David E Meyer, Charles J Fox, Ernest E Moore, Jonathan Morrison, Thomas Scalea, Eileen M Bulger, Kenji Inaba and 3 more

Open access · goldAbstract read
In one paragraph

Article in Trauma surgery & acute care open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Early experience with resuscitative endovascular balloon occlusion of the aorta for unstable pelvic fractures in the Republic of Korea: a multi-institutional study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023
    Article
  3. Ultrasound assessment is useful for evaluating balloon volume of resuscitative endovascular balloon occlusion of the aorta.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Nicholas L JohnsonDepartment of Surgery, The University of Texas Health Science Center at Houston John P and Katherine G McGovern Medical School, Houston, Texas, USA.ORCID 0000-0002-3255-3203
Charles E WadeDepartment of Surgery, The University of Texas Health Science Center at Houston John P and Katherine G McGovern Medical School, Houston, Texas, USA.
Erin E FoxDepartment of Surgery, The University of Texas Health Science Center at Houston John P and Katherine G McGovern Medical School, Houston, Texas, USA.
David E MeyerDepartment of Surgery, The University of Texas Health Science Center at Houston John P and Katherine G McGovern Medical School, Houston, Texas, USA.
Charles J FoxDepartment of Surgery, University of Colorado Denver Health Medical Center, Denver, Colorado, USA.
Ernest E MooreDepartment of Surgery, University of Colorado Denver Health Medical Center, Denver, Colorado, USA.
Jonathan MorrisonShock Trauma Center, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0001-7462-8456
Thomas ScaleaDepartment of Surgery, University of Maryland, Baltimore, Maryland, USA.
Eileen M BulgerDepartment of Surgery, University of Washington, Seattle, Washington, USA.
Kenji InabaDepartment of Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA.
Bryan C MorseDepartment of Surgery, Emory University School of Medicine Atlanta, Atlanta, Georgia, USA.
Laura J MooreDepartment of Surgery, University of Texas McGovern Medical School, Houston, Texas, USA.
Emergent Truncal Hemorrhage Control Study Group
The University of Texas Health Science Center at Houston · USDenver Health Medical Center · USUniversity of Maryland, Baltimore · USEmory University · USUniversity of Southern California · USUniversity of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNon-compressible truncal hemorrhage (NCTH) is the leading cause of preventable death after trauma. Resuscitative endovascular balloon occlusion of the aorta (REBOA) achieves temporary hemorrhage control, supporting cardiac and cerebral perfusion prior to definitive hemostasis. Aortic zone selection algorithms vary among institutions. We evaluated the efficacy of an algorithm for REBOA use.

methodsA multicenter prospective, observational study conducted at six level 1 trauma centers over 12 months. Inclusion criteria were age >15 years with evidence of infradiaphragmatic NCTH needing emergent hemorrhage control within 60 min of ED arrival. An algorithm characterized by the results of focused assessment with sonography in trauma and pelvic X-ray was assessed post hoc for efficacy in a cohort of patients receiving REBOA.

resultsOf the 8166 patients screened, 78 patients had a REBOA placed. 21 patients were excluded, leaving 57 patients for analysis. The algorithm ensures REBOA deployment proximal to hemorrhage source to control bleeding in 98.2% of cases and accurately predicts the optimal REBOA zone in 78.9% of cases. If the algorithm was violated, bleeding was optimally controlled in only 43.8% (p=0.01). Three (75.0%) of the patients that received an inappropriate zone 1 REBOA died, two from multiple organ failure (MOF). All three patients that died with an inappropriate zone 3 REBOA died from exsanguination. DISCUSSION: This algorithm ensures proximal hemorrhage control and accurately predicts the primary source of hemorrhage. We propose a new algorithm that will be more inclusive. A zone 3 REBOA should not be performed when a zone 1 is indicated by the algorithm as 100% of these patients exsanguinated. MOF, perhaps from visceral ischemia in patients with an inappropriate zone 1 REBOA, may have been prevented with zone 3 placement or limited zone 1 occlusion time. LEVEL OF EVIDENCE: Level III.

Indexed as

algorithmaortacontrolhemorrhage

Identifiers

PMID33693060
PMCPMC7907878
OpenAlexW3129369448

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.