Evidence map›Paper›PMID 33693006›Full record

ArticleFrontiers in cell and developmental biology2021

Electroacupuncture Reduces Oocyte Number and Maintains Vascular Barrier Against Ovarian Hyperstimulation Syndrome by Regulating CD200.

Li Chen, Xuan Huang, Li Wang, Cencen Wang, Xu Tang, Minghui Gu, Jun Jing, Rujun Ma, Xie Ge, Bing Yao

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
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  3. Review
  4. Article
  5. Article
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Li ChenCenter of Reproductive Medicine, Affiliated Jinling Hospital, School of Medicine, Nanjing University, Jiangsu, China.
Xuan HuangCenter of Reproductive Medicine, Affiliated Jinling Hospital, School of Medicine, Nanjing University, Jiangsu, China.
Li WangReproductive Medical Center, The Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Shandong, China.
Cencen WangCenter of Reproductive Medicine, Affiliated Jinling Hospital, School of Medicine, Nanjing University, Jiangsu, China.
Xu TangCenter of Reproductive Medicine, Affiliated Jinling Hospital, School of Medicine, Nanjing University, Jiangsu, China.
Minghui GuCenter of Reproductive Medicine, Affiliated Jinling Hospital, School of Medicine, Nanjing University, Jiangsu, China.
Jun JingCenter of Reproductive Medicine, Affiliated Jinling Hospital, School of Medicine, Nanjing University, Jiangsu, China.
Rujun MaCenter of Reproductive Medicine, Affiliated Jinling Hospital, School of Medicine, Nanjing University, Jiangsu, China.
Xie GeCenter of Reproductive Medicine, Affiliated Jinling Hospital, School of Medicine, Nanjing University, Jiangsu, China.
Bing YaoCenter of Reproductive Medicine, Affiliated Jinling Hospital, School of Medicine, Nanjing University, Jiangsu, China.
Nanjing University · CNAffiliated Hospital of Shandong University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ovarian hyperstimulation syndrome (OHSS) is a common complication caused by ovulatory stimulation therapy, which manifests as an increase in ovarian volume, an increase in the number of oocytes retrieved, and increased vascular permeability throughout the body and especially in ovarian tissue. In our previous study, we found that electroacupuncture (EA) could prevent the progression of OHSS, by mainly affecting ovary. However, the specific molecules and the mechanism of this process were still unknown. In order to explore the underlying mechanism, OHSS rat model was established and EA treatment was performed, which was followed by proteomic analysis of ovaries. Results showed a significant increase in the expression level of CD200 in the ovaries of OHSS group treated with EA than those of OHSS group. Clinical data showed that the level of CD200 in follicular fluid was negatively correlated with the number of oocytes retrieved and serum E2 level. Further

Indexed as

anti-inflammationCD200electroacupunctureOHSSvascular barrier

Identifiers

PMID33693006
PMCPMC7938326
OpenAlexW3132818910

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.