Evidence map›Paper›PMID 33692965›Full record

ArticleFrontiers in cellular and infection microbiology2021

Donor Microbiota Composition and Housing Affect Recapitulation of Obese Phenotypes in a Human Microbiota-Associated Murine Model.

Thomas Kaiser, Harika Nalluri, Zhigang Zhu, Christopher Staley

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Human microbiota-associated animal models: a review.Frontiers in cellular and infection microbiology · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Reply to Pantaleón García et al.American journal of physiology. Lung cellular and molecular physiology · 2022
    Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Thomas KaiserDivision of Basic & Translational Research, Department of Surgery, University of Minnesota, Minneapolis, MN, United States.
Harika NalluriDivision of Basic & Translational Research, Department of Surgery, University of Minnesota, Minneapolis, MN, United States.
Zhigang ZhuDivision of Basic & Translational Research, Department of Surgery, University of Minnesota, Minneapolis, MN, United States.
Christopher StaleyDivision of Basic & Translational Research, Department of Surgery, University of Minnesota, Minneapolis, MN, United States.

Funding

Mechanisms of B Cell Pathogenicity in Non-Alcoholic Fatty Liver DiseaseR01DK122056 · NIDDK · UNIVERSITY OF MINNESOTA · PI REVELO, XAVIER · 2019 to 2023
$1.7M
NIDDK NIH HHS R01 DK122056
6 · The paper itself

Abstract

Human microbiota-associated (HMA) mouse models offer a valuable approach to study the role of intestinal microbiota in the development of obesity. In this study, we used an HMA model to evaluate whether engraftment of human obese or lean microbiota, from each of three donors, could recapitulate host phenotypes under conventional and specific-pathogen-free housing. Microbiota engraftment was correlated with donor relative abundances of the class Bacteroidia (Spearman's

Indexed as

HousingMicrobiotaAnimalsDisease Models, AnimalFecal Microbiota TransplantationFecesHumansMiceObesityPhenotypeconventional housingfecal microbiota transplantationhuman microbiota-associatedmouse modelobesityspecific pathogen-free

Identifiers

PMID33692965
PMCPMC7937608

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.