Evidence map›Paper›PMID 33692804›Full record

ArticleFrontiers in immunology2021

A Two-Gene Signature for Tuberculosis Diagnosis in Persons With Advanced HIV.

Vandana Kulkarni, Artur T L Queiroz, Shashi Sangle, Anju Kagal, Sonali Salvi, Amita Gupta, Jerrold Ellner, Dileep Kadam, Valeria C Rolla, Bruno B Andrade and 2 more

Open access · goldAbstract readValidation Study
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Monocyte-Amplified Transcriptional Signatures of Human Diseases.bioRxiv : the preprint server for biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Vandana KulkarniByramjee-Jeejeebhoy Government Medical College-Johns Hopkins University Clinical Research Site (BJGMC-JHU CRS), Pune, India.
Artur T L QueirozInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil.
Shashi SangleByramjee-Jeejeebhoy Government Medical College-Johns Hopkins University Clinical Research Site (BJGMC-JHU CRS), Pune, India.
Anju KagalByramjee-Jeejeebhoy Government Medical College-Johns Hopkins University Clinical Research Site (BJGMC-JHU CRS), Pune, India.
Sonali SalviByramjee-Jeejeebhoy Government Medical College-Johns Hopkins University Clinical Research Site (BJGMC-JHU CRS), Pune, India.
Amita GuptaJohns Hopkins University School of Medicine, Baltimore, MD, United States.
Jerrold EllnerRutgers- New Jersey Medical School, Center for Emerging Pathogens, Newark, NJ, United States.
Dileep KadamByramjee-Jeejeebhoy Government Medical College-Johns Hopkins University Clinical Research Site (BJGMC-JHU CRS), Pune, India.
Valeria C RollaInstituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Bruno B AndradeInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil.
Padmini SalgameRutgers- New Jersey Medical School, Center for Emerging Pathogens, Newark, NJ, United States.
Vidya MaveByramjee-Jeejeebhoy Government Medical College-Johns Hopkins University Clinical Research Site (BJGMC-JHU CRS), Pune, India.
Government Medical College · INFundação Oswaldo Cruz · BRJohns Hopkins University · USRutgers New Jersey Medical SchoolRutgers, The State University of New Jersey · US

Funding

The Johns Hopkins Baltimore-Washington-India Clinical Trials Unit (BWI CTU)UM1AI069465 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Charles W. Flexner, Amita Gupta · 2012 to 2026
$34.1M
NIAID NIH HHS UM1 AI069465
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

TranscriptomeAdultAlgorithmsCohort StudiesFemaleGene Expression ProfilingHIV InfectionsHumansIndiaMaleMiddle AgedMycobacterium tuberculosisReproducibility of ResultsTuberculosisUgandadiagnosisgene signatureHIVtranscriptomicstuberculosis

Identifiers

PMID33692804
PMCPMC7937880
OpenAlexW3130362729

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.